Review article: time to revisit Child‐Pugh score as the basis for predicting drug clearance in hepatic impairment

Author:

El‐Khateeb Eman12ORCID,Darwich Adam S.3ORCID,Achour Brahim1ORCID,Athwal Varinder45ORCID,Rostami‐Hodjegan Amin16ORCID

Affiliation:

1. Centre for Applied Pharmacokinetic Research University of Manchester Manchester UK

2. Clinical Pharmacy Department Faculty of Pharmacy Tanta University Tanta Egypt

3. Logistics and Informatics in Health Care School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH) KTH Royal Institute of Technology Stockholm Sweden

4. Wellcome Centre for Cell‐Matrix Research Division of Diabetes, Endocrinology and Gastroenterology University of Manchester Manchester UK

5. Research and Innovation Division Central Manchester University Hospitals NHS Foundation Trust Manchester UK

6. Certara UK Ltd. (Simcyp Division) Sheffield UK

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Reference106 articles.

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2. Dose Adjustment in Patients with Liver Disease

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4. A proposal for scientific framework enabling specific population drug dosing recommendations

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