Efficacy and safety of linaclotide in patients with irritable bowel syndrome with constipation: Chinese sub‐cohort analysis of a phase III , randomized, double‐blind, placebo‐controlled trial

Author:

Peng Li Hua1,Fang Jing Yuan2,Dai Ning3,Shen Xi Zhong4,Yang You Lin5,Sun Jing6,Yang Yun Sheng1

Affiliation:

1. Department of Gastroenterology and Hepatology, The First Medical Center Chinese PLA General Hospital Beijing China

2. State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology & Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology Shanghai Cancer Institute, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai China

3. Department of Gastroenterology, Sir Run Run Shaw Hospital Zhejiang University School of Medicine Hangzhou Zhejiang Province China

4. Department of Gastroenterology Zhongshan Hospital, Fudan University Shanghai China

5. Department of Gastroenterology The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China

6. Department of Gastroenterology Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China

Funder

AstraZeneca Pharma Poland

Publisher

Wiley

Subject

Gastroenterology

Reference32 articles.

1. Irritable bowel syndrome;Enck P;Nat Rev Dis Primers.,2016

2. Bowel disorders;Mearin F;Gastroenterology.,2016

3. Chronic constipation: new insights, better outcomes?;Schiller LR;Lancet Gastroenterol Hepatol.,2019

4. Study Group of Functional Gastrointestinal Disorders, Study Group of Gastrointestinal Motility, Chinese Society of Gastroenterology, Chinese Medical Association. Chinese expert consensus of irritable bowel syndrome in 2020;Chin J Dig.,2020

5. Irritable bowel syndrome;Ford AC;Lancet.,2020

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