Anesthesia-related neurotoxicity and the developing animal brain is not a significant problem in children
Author:
Affiliation:
1. Department of Anesthesiology and Intensive Care -Pediatric Section; Odense University Hospital; Odense C Denmark
2. Clinical Institute - Anesthesiology; University of Southern Denmark; Odense C Denmark
Publisher
Wiley
Subject
Anesthesiology and Pain Medicine,Pediatrics, Perinatology and Child Health
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/pan.12548/fullpdf
Reference40 articles.
1. Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain;Ikonomidou;Science,1999
2. General anesthesia causes long-lasting disturbances in ultrastructural properties of developing synapses in young rats;Lunardi;Neurotox Res,2010
3. Anesthetics and the developing brain: time for a change in practice? A pro/con debate;Vutskits;Pediatr Anesth,2012
4. General anesthesia: a gateway to modulate synapse formation and neural plasticity?;Vutskits;Anesth Analg,2012
5. Early exposure to common anesthetic agents causes widespread neurodegeneration the developing rat brain and persistent learning deficits;Jevtovic-Todorovic;J Neurosci,2003
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