ROLE OF HYPOTHERMIA IN CEREBRAL PROTECTION IN SURGICAL CORRECTION OF CONGENITAL HEART DEFECTS

Abstract

HighlightsThis article is devoted to a review of studies on the mechanisms of cerebral protection and the effects of hypothermia on the patient. AbstractA large number of surgical corrections of congenital heart defects are performed around the world annually, most of them using cardiopulmonary bypass. This kind of surgery can be a pathological factor for the brain. In some patients, the kind of surgery involves the use of hypothermia. Supposedly, hypothermia should have a neuroprotective effect, however, as recent studies show, this is not always the case. This review is devoted to the mechanisms of the effect of hypothermia on the patient’s body, including not only a decrease in brain metabolism, but also a number of others. Moreover, a review of current works on the use of hypothermia in clinical practice in surgeries that do not require circulatory arrest is presented, along with an analysis of the intra- and postoperative period.