γ-Secretase Exists on the Plasma Membrane as an Intact Complex That Accepts Substrates and Effects Intramembrane Cleavage*
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference54 articles.
1. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
2. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
3. Reconstitution of γ-secretase activity
4. The role of presenilin cofactors in the γ-secretase complex
5. -Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2
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