Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells-Reference-Cited by-同舟云学术

Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells

Published:2017-12 Issue: Volume:110 Page:383-394
ISSN:0278-6915
Container-title:Food and Chemical Toxicology
language:en
Short-container-title:Food and Chemical Toxicology

Author:

Wilsher Nicola E.,Arroo Randolph R.,Matsoukas Minos–Timotheos,Tsatsakis Aristidis M.,Spandidos Demetrios A.,Androutsopoulos Vasilis P.

Funder

De Montfort University

University of Crete

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference62 articles.

1. The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and p53/p21 upregulation;Androutsopoulos;J. Nutr. Biochem.,2013

2. Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism;Androutsopoulos;Breast Cancer Res.,2008

3. Bioactivation of the phytoestrogen diosmetin by CYP1 cytochromes P450;Androutsopoulos;Cancer Lett.,2009

4. Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA–MB–468 breast cancer cells due to CYP1 activation;Androutsopoulos;Oncol. Rep.,2009

5. CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells;Androutsopoulos;Toxicology,2009

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