Assay development and screening of inhibitors targeting the SARS-CoV-2 2′-O-methyltransferase NSP16-Reference-Cited by-同舟云学术

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Assay development and screening of inhibitors targeting the SARS-CoV-2 2′-O-methyltransferase NSP16

Published:2025-12 Issue: Volume:3 Page:100076
ISSN:2773-2169
Container-title:Pharmaceutical Science Advances
language:en
Short-container-title:Pharmaceutical Science Advances

Author:

Cao Mengtong,Trieshmann Carl W.^ORCID,Samrat Subodh Kumar^ORCID,Li Hongmin,Wu Yifei^ORCID,Maher Steven P.,Bae Angela A.,Xie Zhong-Ru,Hogan Robert J.^ORCID,Zheng Y. George^ORCID

Funder

NIH National Institute of General Medical Sciences

National Institutes of Health

National Institutes of Health National Institute of Allergy and Infectious Diseases

Publisher

Elsevier BV

Reference65 articles.

1. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2;Nat. Microbiol.,2020

2. Defining the risk of SARS-CoV-2 variants on immune protection;DeGrace;Nature,2022

3. A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases;Samrat;Emerg. Microb. Infect.,2023

4. Omicron: what makes the latest SARS-CoV-2 variant of concern so concerning?;Jung;J. Virol.,2022

5. Coronaviruses: an overview of their replication and pathogenesis;Fehr;Methods Mol. Biol.,2015

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