A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases
Author:
Affiliation:
1. R. Ken Coit College of Pharmacy, The University of Arizona
2. College of Pharmacy, University of Georgia
3. The University of Arizona
4. The BIO5 Institute, The University of Arizona
Funder
University of Arizona R Ken Coit College of Pharmacy faculty startup fund
National Institutes of Health
Publisher
Informa UK Limited
Link
https://www.tandfonline.com/doi/pdf/10.1080/22221751.2023.2204164
Reference86 articles.
1. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
2. An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19
3. SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801
4. Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
5. Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
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