TDP-43 as a therapeutic target in neurodegenerative diseases: Focusing on motor neuron disease and frontotemporal dementia

Author:

Babazadeh AfshinORCID,Rayner Stephanie L.,Lee Albert,Chung Roger S.

Funder

Macquarie University

Publisher

Elsevier BV

Subject

Neurology,Molecular Biology,Aging,Biochemistry,Biotechnology

Reference103 articles.

1. Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation. Nature;Afroz;Communications,2017

2. Significance and limitation of the pathological classification of TDP‐43 proteinopathy;Arai;Neuropathology,2014

3. Phosphorylated TDP-43 in Alzheimer’s disease and dementia with Lewy bodies;Arai;Acta Neuropathol.,2009

4. HSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation;Arosio;Amyotroph. Lateral Scler. Front. Degener.,2020

5. Structural determinants of the cellular localization and shuttling of TDP-43;Ayala;J. Cell Sci.,2008

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