Pterostilbene alleviates fructose-induced renal fibrosis by suppressing TGF-β1/TGF-β type I receptor/Smads signaling in proximal tubular epithelial cells

Author:

Gu Ting-TingORCID,Chen Tian-Yu,Yang Yan-Zi,Zhao Xiao-Juan,Sun Yang,Li Tu-Shuai,Zhang Dong-Mei,Kong Ling-Dong

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology

Reference55 articles.

1. Potential intervention of alpha- lipoic acid and carnitine on insulin sensitivity and anti-inflammatory cytokines levels in fructose-fed rats, a model of metabolic syndrome;Abdelkarem;J. Diet. Suppl.,2016

2. The antioxidant role of pterostilbene in streptozotocin-nicotinamide-induced type 2 diabetes mellitus in Wistar rats;Amarnath Satheesh;J. Pharm. Pharmacol.,2006

3. Fructose induces tubulointerstitial injury in the kidney of mice;Aoyama;Biochem. Biophys. Res. Commun.,2012

4. Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2;Bhakkiyalakshmi;Br. J. Pharmacol.,2014

5. Improved mitochondrial function underlies the protective effect of pirfenidone against tubulointerstitial fibrosis in 5/6 nephrectomized rats;Chen;PLoS One,2013

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