Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors-Reference-Cited by-同舟云学术

Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors

Published:2012-06 Issue:12 Volume:22 Page:4133-4138
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chu Lin,Armstrong Helen M.,Chang Linda L.,Cheng Amy F.,Colwell Lawrence,Cui Jisong,Evans Jilly,Galka Amy,Goulet Mark T.,Hayes Nancy,Lo Jane,Menke John,Ok Hyun O.,Ondeyka Debra L.,Patel Minal,Quaker Grace M.,Sings Heather,Witkin Stephanie L.,Zhao Annie,Ujjainwalla Feroze

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference9 articles.

1. Leukotriene Biosynthesis Inhibitors

2. Leukotriene modifiers as potential therapeutics for cardiovascular disease

3. Identification and isolation of a membrane protein necessary for leukotriene production

4. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

5. Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein

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