Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein-Reference-Cited by-同舟云学术

Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein

Published:2008-03 Issue:6 Volume:18 Page:2023-2027
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Macdonald Dwight,Brideau Christine,Chan Chi Chung,Falgueyret Jean-Pierre,Frenette Richard,Guay Jocelyne,Hutchinson John H.,Perrier Hélène,Prasit Peptiboon,Riendeau Denis,Tagari Philip,Thérien Michel,Young Robert N.,Girard Yves

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. Leukotriene modifiers as potential therapeutics for cardiovascular disease

2. Leukotriene Biosynthesis Inhibitors

3. The 5 lipoxygenase system in the vasculature: Emerging role in health and disease

4. Regulation of 5-lipoxygenase enzyme activity

5. Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase-Activating Protein

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Superelectrophilic Nonclassical Carbocations;The Journal of Organic Chemistry;2024-07-02

2. Combined Machine Learning and GRID-Independent Molecular Descriptor (GRIND) Models to Probe the Activity Profiles of 5-Lipoxygenase Activating Protein Inhibitors;Frontiers in Pharmacology;2022-03-01

3. Fingerprint‐based computational models of 5‐lipo‐oxygenase activating protein inhibitors: Activity prediction and structure clustering;Chemical Biology & Drug Design;2020-09

4. Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesis;European Journal of Medicinal Chemistry;2018-06

5. Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening;Scientific Reports;2017-02-20