1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1-Reference-Cited by-同舟云学术

1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1

Published:2005-02 Issue:4 Volume:15 Page:1217-1220
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wattanasin Sompong,Kallen Joerg,Myers Stewart,Guo Qin,Sabio Michael,Ehrhardt Claus,Albert Rainer,Hommel Ulrich,Weckbecker Gisbert,Welzenbach Karl,Weitz-Schmidt Gabriele

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

1. Therapeutic antagonists and conformational regulation of integrin function

2. Small Molecule Integrin Antagonists that Bind to the β2 Subunit I-like Domain and Activate Signals in One Direction and Block Them in the Other

3. Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: designing peptide and small molecule inhibitors

4. Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation

5. Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases

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