Therapeutic antagonists and conformational regulation of integrin function
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd1174.pdf
Reference111 articles.
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3. Humphries, M. J. Integrin structure. Biochem. Soc. Trans. 28, 311–339 (2000).
4. Shimaoka, M., Takagi, J. & Springer, T. A. Conformational regulation of integrin structure and function. Annu. Rev. Biophys. Biomol. Struct. 31, 485–516 (2002). Comprehensively reviews conformational changes of integrins with emphasis on the conformational regulation of ligand binding by I domains.
5. Curley, G. P., Blum, H. & Humphries, M. J. Integrin antagonists. Cell. Mol. Life Sci. 56, 427–441 (1999).
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