Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists-Reference-Cited by-同舟云学术

Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists

Published:2005-01 Issue:2 Volume:15 Page:435-438
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Merriman Gregory H.,Ma Liang,Shum Patrick,McGarry Daniel,Volz Frank,Sabol Jeffrey S.,Gross Alexandre,Zhao Zhicheng,Rampe David,Wang Lin,Wirtz-Brugger Friederike,Harris Bruce A.,Macdonald Douglas

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference16 articles.

1. The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

2. Hit-to-Lead studies: The discovery of potent adamantane amide P2X7 receptor antagonists

3. Novel P2X7 receptor antagonists

4. Synthesis and Biological Activity of N-Arylpiperazine-Modified Analogues of KN-62, a Potent Antagonist of the Purinergic P2X7 Receptor

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