Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation-Reference-Cited by-同舟云学术

Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation

Published:2021-02-09 Issue:4 Volume:64 Page:2272-2290
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Calzaferri Francesco¹^ORCID,Narros-Fernández Paloma¹²,de Pascual Ricardo¹,de Diego Antonio M.G.¹,Nicke Annette³,Egea Javier¹²^ORCID,García Antonio G.¹²,de los Ríos Cristóbal¹²^ORCID

Affiliation:

1. Instituto-Fundación Teófilo Hernando and Departamento de Farmacología, Facultad de Medicina, Universidad Autónoma de Madrid, C/ Arzobispo Morcillo 4, 28029 Madrid, Spain

2. Instituto de Investigación Sanitaria, Hospital Universitario de La Princesa, C/ Diego de León, 62—1a Planta, 28006 Madrid, Spain

3. Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität München, 80336 Munich, Germany

Funder

Ministerio de Ciencia e Innovaci?n

European Regional Development Fund

Deutsche Forschungsgemeinschaft

Instituto de Salud Carlos III

Fundaci?n Te?filo Hernando

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine