Structural determinants for histamine H1 affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs-Reference-Cited by-同舟云学术

Structural determinants for histamine H1 affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs

Published:2009-09 Issue:17 Volume:19 Page:5043-5047
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Aslanian Robert,Piwinski John J.,Zhu Xiaohong,Priestley Tony,Sorota Steve,Du Xiao-Yi,Zhang Xue-Song,McLeod Robbie L.,West Robert E.,Williams Shirley M.,Hey John A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience

2. Safety of Non-Antiarrhythmic Drugs that Prolong the QT Interval or Induce Torsade de Pointes

3. Drug induced QT prolongation and torsades de pointes

4. Cardiotoxicity of new antihistamines and cisapride

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