Picomolar inhibitor of reverse transcriptase featuring significantly improved metabolic stability
Author:
Funder
Fudan University
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
General Pharmacology, Toxicology and Pharmaceutics
Reference32 articles.
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3. Structure-based bioisosterism yields HIV-1 NNRTIs with improved drug-resistance profiles and favorable pharmacokinetic properties;Kang;J Med Chem,2020
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3. Improving the anti-HIV-1 activity and solubility of poorly water-soluble DAPYs by heteroaromatic replacement strategy: From naphthalene-DAPYs to quinoline-DAPYs;Bioorganic Chemistry;2023-11
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