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Recent advances on the intervention sites targeting USP7-MDM2-p53 in cancer therapy

  • Published:2021-11 Issue: Volume:116 Page:105273
  • ISSN:0045-2068
  • Container-title:Bioorganic Chemistry
  • language:en
  • Short-container-title:Bioorganic Chemistry

Author:

Harakandi Chrisanta,Nininahazwe Lauraine,Xu Haiwei,Liu Bingrui,He Chenghua,Zheng Yi-Chao,Zhang Hang

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hebei Province

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference100 articles.

1. USP7: Structure, substrate specificity, and inhibition;Pozhidaeva;DNA Repair (Amst),2019

2. Emerging insights into HAUSP (USP7) in physiology, cancer and other diseases;Bhattacharya;Signal Transduct Target Ther,2018

3. The past, present and future of potential small-molecule drugs targeting p53-MDM2/MDMX for cancer therapy;Liu;Eur. J. Med. Chem.,2019

4. From discovery to bedside: targeting the ubiquitin system;Wertz;Cell Chem. Biol.,2019

5. Defining the human deubiquitinating enzyme interaction landscape;Sowa;Cell,2009

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