3-Substituted-4-hydroxycoumarin as a new scaffold with potent CDK inhibition and promising anticancer effect: Synthesis, molecular modeling and QSAR studies

Author:

Abdel Latif Nehad A.,Batran Rasha Z.,Khedr Mohammed A.,Abdalla Mohamed M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference55 articles.

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3. Principles of CDK regulation;Morgan;Nature,1995

4. Cancer cell cycles;Sherr;Science,1996

5. Cdk1 and Cdk2 complexes (cyclin dependent kinases) in apoptosis: a role beyond the cell cycle;Golsteyn;Cancer Lett.,2005

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