Combined nucleus pulposus augmentation and annulus fibrosus repair prevents acute intervertebral disc degeneration after discectomy-Reference-Cited by-同舟云学术

Combined nucleus pulposus augmentation and annulus fibrosus repair prevents acute intervertebral disc degeneration after discectomy

Published:2020-03-11 Issue:534 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Sloan Stephen R.¹^ORCID,Wipplinger Christoph²^ORCID,Kirnaz Sertaç²,Navarro-Ramirez Rodrigo²,Schmidt Franziska²,McCloskey Duncan¹^ORCID,Pannellini Tania³,Schiavinato Antonella⁴,Härtl Roger²,Bonassar Lawrence J.¹⁵^ORCID

Affiliation:

1. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.

2. Department of Neurological Surgery, Weill Cornell Medical College, New York, NY 10065, USA.

3. Pathology and Laboratory Medicine, Hospital for Special Surgery, New York, NY 10065, USA.

4. Fidia Farmaceutici S.p.A, Abano Terme, PD 35031, Italy.

5. Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA.

Abstract

Tissue-engineered therapies targeting the nucleus pulposus and annulus fibrosus prevent intervertebral disc degeneration after discectomy in sheep.

Funder

Colin MacDonald Fund

NYSTEM

Cornell University Biotechnology Resource Center NIH Grant

Cornell University CTSC NIH/NCATS

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference82 articles.

1. Degenerative Lumbar Disc and Facet Disease in Older Adults

2. What is Intervertebral Disc Degeneration, and What Causes It?

3. Intervertebral disc (IVD): Structure, degeneration, repair and regeneration

4. Aggrecan degradation in human intervertebral disc and articular cartilage

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