Diversification of the antigen-specific T cell receptor repertoire after varicella zoster vaccination-Reference-Cited by-全球学者库

Diversification of the antigen-specific T cell receptor repertoire after varicella zoster vaccination

Published:2016-03-30 Issue:332 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Qi Qian¹²,Cavanagh Mary M.¹²,Le Saux Sabine¹²,NamKoong Hong¹²,Kim Chulwoo¹²,Turgano Emerson²,Liu Yi³,Wang Chen⁴,Mackey Sally⁵,Swan Gary E.⁶,Dekker Cornelia L.⁵,Olshen Richard A.³⁷,Boyd Scott D.⁴,Weyand Cornelia M.¹²,Tian Lu⁷,Goronzy Jörg J.¹²

Affiliation:

1. Division of Immunology and Rheumatology, Department of Medicine, Stanford University, Stanford, CA 94305, USA.

2. Department of Medicine, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA.

3. Department of Statistics, Stanford University, Stanford, CA 94305, USA.

4. Department of Pathology, Stanford University, Stanford, CA 94305, USA.

5. Division of Infectious Diseases, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.

6. Department of Medicine, Stanford Prevention Research Center, Stanford University, Stanford, CA 94305, USA.

7. Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.

Abstract

Adult vaccination with an attenuated herpes zoster virus broadens the T cell receptor repertoire without reinforcing clonal dominance.

Funder

NIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference41 articles.

1. CD4 T Cell Immunity Is Critical for the Control of Simian Varicella Virus Infection in a Nonhuman Primate Model of VZV Infection

2. The Incidence of Herpes Zoster

3. T-cell quality in memory and protection: implications for vaccine design

4. Direct Link Between mhc Polymorphism, T Cell Avidity, and Diversity in Immune Defense

5. High-throughput sequencing insights into T-cell receptor repertoire diversity in aging

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