Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis-Reference-Cited by-同舟云学术

Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis

Published:2018-02-07 Issue:427 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Coleman Mitchell C.¹^ORCID,Goetz Jessica E.¹^ORCID,Brouillette Marc J.¹^ORCID,Seol Dongrim¹^ORCID,Willey Michael C.¹,Petersen Emily B.¹^ORCID,Anderson Hope D.²,Hendrickson Nathan R.¹,Compton Jocelyn¹^ORCID,Khorsand Behnoush¹,Morris Angie S.¹^ORCID,Salem Aliasger K.¹^ORCID,Fredericks Douglas C.¹^ORCID,McKinley Todd O.³^ORCID,Martin James A.¹^ORCID

Affiliation:

1. University of Iowa, Iowa City, IA 52242, USA.

2. Wellesley College, Boston, MA 02481, USA.

3. Indiana University Health Methodist Hospital Orthopaedic Trauma Service, Indianapolis, IN 46202, USA.

Abstract

Inhibiting mitochondrial oxidant production after surgical fixation of an intra-articular fracture prevents osteoarthritis in a porcine model.

Funder

U.S. Department of Defense

NIH Clinical Center

Department of Defense

Publisher

American Association for the Advancement of Science (AAAS)