Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease-Reference-Cited by-同舟云学术

Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease

Published:2020-07-03 Issue:49 Volume:5 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Vogt Matthew R.¹^ORCID,Fu Jianing²^ORCID,Kose Nurgun³,Williamson Lauren E.⁴^ORCID,Bombardi Robin³^ORCID,Setliff Ian⁵,Georgiev Ivelin S.³⁴,Klose Thomas²^ORCID,Rossmann Michael G.²,Hurst Brett L.⁶^ORCID,Tarbet E. Bart⁶^ORCID,Bochkov Yury A.⁷^ORCID,Gern James E.⁷⁸,Kuhn Richard J.²^ORCID,Crowe James E.¹³⁴⁵^ORCID

Affiliation:

1. Department of Pediatrics (Infectious Diseases), Vanderbilt University Medical Center, Nashville, TN, USA.

2. Department of Biological Sciences and Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, IN, USA.

3. Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA.

4. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.

5. Program in Chemical and Physical Biology, Vanderbilt University, Nashville, TN, USA.

6. Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA.

7. Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.

8. Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.

Abstract

A human monoclonal antibody shows potential to prevent or treat acute flaccid myelitis associated with enterovirus D68 infection.

Funder

National Heart, Lung, and Blood Institute

NIH Office of the Director

National Institute of Allergy and Infectious Diseases

PIDS-St. Jude Research Hospital’s Fellow Program in Basic & Translational Research fellowship

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference59 articles.

1. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children

2. Clusters of acute respiratory illness associated with human enterovirus 68—Asia, Europe, and United States, 2008-2010;Centers for Disease Control and Prevention (CDC);MMWR Morb. Mortal. Wkly. Rep.,2011

3. Severe respiratory illness associated with a nationwide outbreak of enterovirus D68 in the USA (2014): a descriptive epidemiological investigation

4. European surveillance for enterovirus D68 during the emerging North-American outbreak in 2014

5. Acute Flaccid Myelitis in the United States, August–December 2014: Results of Nationwide Surveillance

Cited by 33 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Human genetic errors of immunity illuminate an adaptive arsenal model of rapid defenses;Trends in Immunology;2024-01

2. Identification of four neutralizing antigenic sites on the enterovirus D68 capsid;Journal of Virology;2023-12-21

3. In vitro and in vivo models for the study of EV-D68 infection;Pathology;2023-12

4. Comprehensive profiling of neutralizing polyclonal sera targeting coxsackievirus B3;Nature Communications;2023-10-12

5. In silico epitope prediction and evolutionary analysis reveals capsid mutation patterns for enterovirus B;PLOS ONE;2023-08-28