Induced pluripotent stem cells in medicine and biology-Reference-Cited by-同舟云学术

Induced pluripotent stem cells in medicine and biology

Published:2013-06-15 Issue:12 Volume:140 Page:2457-2461
ISSN:1477-9129
Container-title:Development
language:en
Short-container-title:

Author:

Takahashi Kazutoshi¹,Yamanaka Shinya¹²

Affiliation:

1. Center for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan

2. Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA

Abstract

Differentiated cells can be reprogrammed to pluripotency and other cell fates by treatment with defined factors. The discovery of induced pluripotent stem cells (iPSCs) has opened up unprecedented opportunities in the pharmaceutical industry, in the clinic and in laboratories. In particular, the medical applications of human iPSCs in disease modeling and stem cell therapy have been progressing rapidly. The ability to induce cell fate conversion is attractive not only for these applications, but also for basic research fields, such as development, cancer, epigenetics and aging.

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Link

http://journals.biologists.com/dev/article-pdf/140/12/2457/1319700/2457.pdf

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