Home High-Flow Nasal Cannula Oxygen Therapy for Stable Hypercapnic COPD: A Randomized Clinical Trial

Author:

Nagata Kazuma1,Horie Takeo2,Chohnabayashi Naohiko3,Jinta Torahiko3,Tsugitomi Ryosuke3,Shiraki Akira4,Tokioka Fumiaki5,Kadowaki Toru6ORCID,Watanabe Akira7,Fukui Motonari8,Kitajima Takamasa8,Sato Susumu9ORCID,Tsuda Toru10,Kishimoto Nobuhito11,Kita Hideo12,Mori Yoshihiro13,Nakayama Masayuki14,Takahashi Kenichi15,Tsuboi Tomomasa16,Yoshida Makoto17,Hataji Osamu18,Fuke Satoshi19,Kagajo Michiko4,Nishine Hiroki20,Kobayashi Hiroyasu21,Nakamura Hiroyuki22,Okuda Miyuki23ORCID,Tachibana Sayaka24,Takata Shohei25,Osoreda Hisayuki26,Minami Kenichi27,Nishimura Takashi28,Ishida Tadashi5,Terada Jiro29,Takeuchi Naoko30,Kohashi Yasuo31,Inoue Hiromasa32,Nakagawa Yoko33,Kikuchi Takashi33,Tomii Keisuke1

Affiliation:

1. Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan;

2. Department of Respiratory Medicine, Japanese Red Cross Maebashi Hospital, Maebashi, Gunma, Japan;

3. Division of Pulmonary Medicine, Thoracic Center, St. Luke’s International Hospital, Chuo-ku, Tokyo, Japan;

4. Department of Respiratory Medicine, Ogaki Municipal Hospital, Ogaki, Gifu, Japan;

5. Department of Respiratory Medicine, Kurashiki Central Hospital, Kurashiki, Okayama, Japan;

6. Department of Pulmonary Medicine, National Hospital Organization Matsue Medical Center, Matsue, Shimane, Japan;

7. Department of Respiratory Medicine, National Hospital Organization Ehime Medical Center, Toon, Ehime, Japan;

8. Respiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Osaka, Japan;

9. Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan;

10. Kirigaoka Tsuda Hospital, Kitakyushu, Fukuoka, Japan;

11. Department of Respiratory Medicine, Takamastu Municipal Hospital, Takamatsu, Kagawa, Japan;

12. Department of Respiratory Medicine, Takatsuki Red Cross Hospital, Takatsuki, Osaka, Japan;

13. Department of Respiratory Medicine, KKR Takamatsu Hospital, Takamatsu, Kagawa, Japan;

14. Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan;

15. Department of Respiratory Medicine, Kishiwada City Hospital, Kishiwada, Osaka, Japan;

16. Department of Respiratory Medicine, National Hospital Organization Minami Kyoto Hospital, Joyo, Kyoto, Japan;

17. Department of Respiratory Medicine, National Hospital Organization Fukuoka National Hospital, Fukuoka, Fukuoka, Japan;

18. Respiratory Center, Matsusaka Municipal Hospital, Matsusaka, Mie, Japan;

19. Department of Respiratory Medicine, KKR Sapporo Medical Center, Sapporo, Hokkaido, Japan;

20. Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan;

21. Respiratory Center, Suzuka General Hospital, Suzuka, Mie, Japan;

22. Department of Respiratory Medicine, Sakaide City Hospital, Sakaide, Kagawa, Japan;

23. Osaka Anti-Tuberculosis Association Osaka Hospital, Neyagawa, Osaka, Japan;

24. Department of Respiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan;

25. Department of Respiratory Medicine, National Hospital Organization Fukuokahigashi Medical Center, Koga, Fukuoka, Japan;

26. Department of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Yamaguchi, Japan;

27. Department of Respiratory Medicine, Ishikiriseiki Hospital, Higashi-osaka, Osaka, Japan;

28. Department of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Kyoto, Japan;

29. Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan;

30. Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai, Osaka, Japan;

31. Department of Respiratory Medicine, HARUHI Respiratory Medical Hospital, Kiyosu, Aichi, Japan;

32. Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Kagoshima, Japan; and

33. Division of Medical Statistics, Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Hyogo, Japan

Funder

Teijin Pharma

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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