SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022-Reference-Cited by-同舟云学术

SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022

Published:2022-06-02 Issue:22 Volume:27 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Sievers Claudia¹²³⁴,Zacher Benedikt¹⁴^ORCID,Ullrich Alexander⁴,Huska Matthew⁵,Fuchs Stephan⁵,Buda Silke⁴,Haas Walter⁴,Diercke Michaela⁴,an der Heiden Matthias⁴,Kröger Stefan⁴

Affiliation:

1. These authors contributed equally to this work and share first authorship

2. European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden

3. Postgraduate Training for Applied Epidemiology (PAE), Robert Koch Institute, Berlin, Germany

4. Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany

5. Department of Genome Sequencing and Genomic Epidemiology, Robert Koch Institute, Berlin, Germany

Abstract

German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases’ proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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