<b>Metabolic profiling of gemcitabine- and paclitaxel-treated immortalized human pancreatic cell lines with K-RAS</b><sup><b>G12D </b></sup>-Reference-Cited by-同舟云学术

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Metabolic profiling of gemcitabine- and paclitaxel-treated immortalized human pancreatic cell lines with K-RAS^G12D

Published:2017 Issue:1 Volume:38 Page:29-40
ISSN:0388-6107
Container-title:Biomedical Research
language:en
Short-container-title:Biomed. Res.

Author:

TODAKA Akiko¹²³,UMEHARA Rina⁴,SASAKI Keiko⁵,SERIZAWA Masakuni⁴,URAKAMI Kenichi⁶,KUSUHARA Masatoshi⁴⁷,YAMAGUCHI Ken²,YASUI Hirofumi¹

Affiliation:

1. Division of Gastrointestinal Oncology, Shizuoka Cancer Center

2. Shizuoka Cancer Center

3. Department of Surgery, Keio University Graduate School of Medicine

4. Drug Discovery and Development Division, Shizuoka Cancer Center Research Institute

5. Division of Pathology, Shizuoka Cancer Centre

6. Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute

7. Regional Resources Division, Shizuoka Cancer Center Research Institute

Publisher

Biomedical Research Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://www.jstage.jst.go.jp/article/biomedres/38/1/38_29/_pdf

Reference39 articles.

1. 1 Biankin AV, Waddell N, Kassahn KS, Gingras MC, Muthuswamy LB, et al. (2012) Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 491, 399–405.

2. 2 Bryant KL, Mancias JD, Kimmelman AC and Der CJ (2014) KRAS: feeding pancreatic cancer proliferation. Trends Biochem Sci 39, 91–100.

3. 3 Burris HA 3rd, Moore MJ, Andersen J, Green MR, Rothenberg ML, et al. (1997) Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 15, 2403–2413.

4. 4 Campbell PM, Groehler AL, Lee KM, Ouellette MM, Khazak V and Der CJ (2007) K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling. Cancer Res 67, 2098–2106.

5. 5 Chen N, Brachmann C, Liu X, Pierce DW, Dey J, Kerwin WS, Li Y, Zhou S, Hou S, Carleton M, Klinghoffer RA, Palmisano M and Chopra R (2015) Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tumor penetration. Cancer Chemother Pharmacol 76, 699–712.

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