Identification of natural compound garcinone E as a novel autophagic flux inhibitor with anticancer effect in nasopharyngeal carcinoma cells

Author:

Wei Dan1,Wang Luolin2,Lei Shunmei1,Zhang Han1,Dong Caihua134,Ke Yao56,Su Yuting56,Chen Xiaoying56,Xia Lianping56,Kong Xiaoyang1,Yin Fuqiang56,Liu Xia134

Affiliation:

1. Key Laboratory of Longevity and Ageing-Related Disease of Chinese Ministry of Education, Center for Translational Medicine and School of Preclinical Medicine, Guangxi Medical University, Nanning, Guangxi, P.R. China

2. Department of Gastroenterology, Shenzhen People’s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, P.R. China

3. Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, Nanning, Guangxi, P.R. China

4. Department of Human Anatomy, Institute of Neuroscience and Guangxi Key Laboratory of Brain Science, School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, P.R. China

5. Key Laboratory of High-Incidence-Tumour Prevention and Treatment, Guangxi Medical University, Ministry of Education, Nanning, Guangxi, P.R. China)

6. Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, P.R. China

Funder

National Natural Science Foundation of China

Xinghu Scholars Program of Guangxi Medical University Innovation

Innovation Project of Guangxi Graduate Education

Natural Science Foundation of Guangxi Zhuang Autonomous Region, Advanced Innovation Teams

Publisher

Informa UK Limited

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,General Medicine

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