Advances in anti-fungal therapies
Author:
Publisher
Springer Science and Business Media LLC
Subject
Veterinary (miscellaneous),Agronomy and Crop Science,Applied Microbiology and Biotechnology,Microbiology
Link
https://link.springer.com/content/pdf/10.1007/s11046-021-00560-2.pdf
Reference65 articles.
1. Warrilow AG, Hull CM, Parker JE, Garvey EP, Hoekstra WJ, Moore WR, et al. The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme. Antimicrob Agents Chemother. 2014;58(12):7121–7. https://doi.org/10.1128/AAC.03707-14.
2. Schell WA, Jones AM, Garvey EP, Hoekstra WJ, Schotzinger RJ, Alexander BD. Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds. Antimicrob Agents Chemother. 2017;61(3). https://doi.org/10.1128/AAC.01817-16.
3. Warrilow AGS, Parker JE, Price CL, Garvey EP, Hoekstra WJ, Schotzinger RJ et al. The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51. Antimicrob Agents Chemother. 2017; https://doi.org/10.1128/AAC.00333-17.
4. Shubitz LF, Trinh HT, Galgiani JN, Lewis ML, Fothergill AW, Wiederhold NP, et al. Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models. Antimicrob Agents Chemother. 2015;59(12):7249–54. https://doi.org/10.1128/AAC.00593-15.
5. Break TJ, Desai JV, Natarajan M, Ferre EMN, Henderson C, Zelazny AM, et al. VT-1161 protects mice against oropharyngeal candidiasis caused by fluconazole-susceptible and -resistant Candida albicans. J Antimicrob Chemother. 2018;73(1):151–5. https://doi.org/10.1093/jac/dkx352.
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