Effect of Lifestyle Intervention on the Occurrence of Metabolic Syndrome and its Components in the Finnish Diabetes Prevention Study-Reference-Cited by-同舟云学术

Effect of Lifestyle Intervention on the Occurrence of Metabolic Syndrome and its Components in the Finnish Diabetes Prevention Study

Published:2008-04-01 Issue:4 Volume:31 Page:805-807
ISSN:0149-5992
Container-title:Diabetes Care
language:en
Short-container-title:

Author:

Ilanne-Parikka Pirjo¹²,Eriksson Johan G.³⁴,Lindström Jaana³,Peltonen Markku³,Aunola Sirkka⁵,Hämäläinen Helena⁶,Keinänen-Kiukaanniemi Sirkka⁷⁸⁹,Laakso Mauri⁷⁸¹⁰,Valle Timo T.³,Lahtela Jorma¹¹,Uusitupa Matti¹²,Tuomilehto Jaakko³⁴,

Affiliation:

1. Diabetes Center, Finnish Diabetes Association, Tampere, Finland

2. Department of Research Administration, Pirkanmaa Hospital District, Tampere, Finland

3. Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland

4. Department of Public Health, University of Helsinki, Helsinki, Finland

5. Department of Health and Functional Capacity, Laboratory for Population Research, National Public Health Institute, Turku, Finland

6. Research Department, Social Insurance Institution, Turku, Finland

7. Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland

8. Department of Sport Medicine, Oulu Deaconess Institute, Oulu, Finland

9. Oulu Health Centre, Oulu, Finland

10. Unit of General Practice, Oulu University Hospital, Oulu, Finland

11. Department of Internal Medicine, Tampere University Hospital, Tampere, Finland

12. Department of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland

Abstract

OBJECTIVE—The aim of this secondary analysis of the Finnish Diabetes Prevention Study was to assess the effects of lifestyle intervention on metabolic syndrome and its components. RESEARCH DESIGN AND METHODS—A total of 522 middle-aged overweight men and women with impaired glucose tolerance were randomized into an individualized lifestyle intervention group or a standard care control group. National Cholesterol Education Program criteria were used for the definition of metabolic syndrome. RESULTS—At the end of the study, with a mean follow-up of 3.9 years, we found a significant reduction in the prevalence of metabolic syndrome in the intervention group compared with the control group (odds ratio [OR] 0.62 [95% CI 0.40–0.95]) and in the prevalence of abdominal obesity (0.48 [0.28–0.81]). CONCLUSIONS—The results suggest that lifestyle intervention may also reduce risk of cardiovascular disease in the long run.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://diabetesjournals.org/care/article-pdf/31/4/805/598511/zdc00408000805.pdf

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