Prevalence and Factors Associated with Metabolic Syndrome among Non-Diabetic Saudi Adults: A Cross-Sectional Study

Author:

Eldakhakhny Basmah123ORCID,Enani Sumia234ORCID,Jambi Hanan234,Ajabnoor Ghada123ORCID,Al-Ahmadi Jawaher235,Al-Raddadi Rajaa236ORCID,Alsheikh Lubna7,Abdulaal Wesam H.7ORCID,Gad Hoda18ORCID,Borai Anwar29,Bahijri Suhad123ORCID,Tuomilehto Jaakko21011

Affiliation:

1. Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah 22252, Saudi Arabia

2. Saudi Diabetes Research Group, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 22252, Saudi Arabia

3. Food, Nutrition, and Lifestyle Research Unit, King Fahd for Medical Research Center, King Abdulaziz University, Jeddah 22252, Saudi Arabia

4. Department of Food and Nutrition, Faculty of Human Sciences and Design, King Abdulaziz University, Jeddah 22252, Saudi Arabia

5. Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah 22252, Saudi Arabia

6. Department of Community Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah 22252, Saudi Arabia

7. Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia

8. Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Alexandria University, Alexandria 21561, Egypt

9. King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Jeddah 22384, Saudi Arabia

10. Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland

11. Public Health Promotion Unit, Finnish Institute for Health and Welfare, FI-00271 Helsinki, Finland

Abstract

(1) Introduction: given the high prevalence of metabolic syndrome (MetS) in Saudi Arabia, especially in Jeddah, this study aims to understand the dietary and lifestyle-related risk factors among Jeddah’s non-diabetic adults. (2) Material and Methods: Employing a cross-sectional design, non-diabetic adults were sourced from public healthcare centers. Demographics, lifestyle, and dietary habits were surveyed. Blood pressure, anthropometrics, and fasting blood samples measuring plasma glucose, serum triglycerides, and HDL cholesterol were collected. The age cut-off for MetS was ascertained using the receiver operating characteristic curve. Variables influencing MetS were evaluated using univariate logistic regression, and consequential factors underwent multivariate analysis, adjusted for age and sex. (3) Results: Among 1339 participants, 16% had MetS, with age being the strongest predictor (p < 0.001). The optimal age cut-off was 32 years. For those <32, elevated BP in men and waist circumference (WC) in women were most prevalent. For those >32, elevated WC was dominant in both sexes. Univariate logistic regression revealed that higher income and education correlated with lower MetS prevalence, while marriage and smoking were risk factors. Adjusting for age and sex, only very high income had a significant low-risk association (p = 0.034). (4) Conclusion: MetS is notable in the studied group, with age as the pivotal predictor. High income reduces MetS risk, while marital status and smoking could increase it. Since this was a cross-sectional study, cohort studies are needed to validate our findings.

Funder

King Abdulaziz University (KAU), Jeddah, Saudi Arabia

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

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