2020年度中国病理学领域高价值论文TOP100
互联网时代，文献资料浩如烟海。如何快速发现本领域的高价值论文，是每个科研研究人员的愿望。但以往对一篇论文的价值评估，是通过期刊影响因子或被引频次来判断，这种采用单一指标评判论文的学术价值因有失偏颇而广受诟病。北京同舟云网络信息技术有限公司创立了一种优选算法，综合考虑Metrics 期刊评分、论文被引频次、文献类型以及论文发表时间等多种因素，对每篇论文进行深度解析与计算，并赋予分值，以量化每篇论文的学术价值和影响力。本推荐表是在系统全面准确地统计中国机构作者发表的病理学领域国际论文的基础上，对每篇论文依上述方法进行计算并赋分排名而得出的，供相关学者学习、评判、参考和借鉴。
序号 | 年份 | 标题 | 期刊 | 主要完成人 | 论文评分 | 1 |
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| 2 | 2020 | Hepatic involvement in COVID20209 patients: Pathology, pathogenesis, and clinical implications | J MED VIROL | 肖书渊,武汉大学,中南医院,病理科; | 65422.24 | 3 | 2020 | Renal histopathological analysis of 26 postmortem fi ndings of patients with COVID20209 in China | KIDNEY INT | 聂秀,华中科技大学同济医学院,附属协和医院,病理科; | 43607.2 | 4 | 2020 | Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID20209) Pneumonia in Two Patients With Lung Cancer | J THORAC ONCOL | 肖书渊,武汉大学,中南医院,病理科; | 41945.12 | 5 | 2020 | Pathological study of the 2019 novel coronavirus disease (COVID20209) through postmortem core biopsies | MODERN PATHOL | 肖书渊,武汉大学,中南医院,病理科; | 23656.8 | 6 | 2020 | SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID20209 | J HEPATOL | 赵景民,解放军总医院第五医学中心,病理诊断与研究中心; | 11229.12 | 7 | 2020 | Structural basis of GPBAR activation and bile acid recognition | NATURE | 张岩,浙江大学附属邵逸夫医院 | 7915.2 | 8 | 2020 | SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation | SCIENCE | 卞修武,陆军军医大学,西南医院,病理科; | 7335.2 | 9 | 2020 | Architecture of the photosynthetic complex from a green sulfur bacterium | SCIENCE | 张岩,浙江大学附属邵逸夫医院 | 7271.2 | 10 | 2020 | Risk of nosocomial transmission of coronavirus disease 2019: an experience in a general ward setting in Hong Kong | J HOSP INFECT | Lung, David Christopher,香港大学; | 6928.64 | 11 | 2020 | PD2020/PD-L1 pathway: current researches in cancer | AM J CANCER RES | 韩言言,大连医科大学; | 6716.32 | 12 | 2020 | Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID20209 patients | EBIOMEDICINE | 卞修武,陆军军医大学,西南医院,病理科; | 6444.8 | 13 | 2020 | Pathological Findings in the Testes of COVID20209 Patients: Clinical Implications | EUR UROL FOCUS | 聂秀,华中科技大学同济医学院,附属协和医院,病理科; | 6144.16 | 14 | 2020 | Genomic and Transcriptomic Characterization of Natural Killer T Cell Lymphoma | CANCER CELL | 赵维莅,上海交通大学,瑞金医院,病理科; | 5985.12 | 15 | 2020 | Nanostructured Substrates for Detection and Characterization of Circulating Rare Cells: From Materials Research to Clinical Applications | ADV MATER | 柯尊富,中山大学,附属第一医院,病理科; | 5919.68 | 16 | 2020 | Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission | CELL STEM CELL | 王建枝,华中科技大学,基础医学院病理生理学系,; | 5750.88 | 17 | 2020 | The phosphatase PAC1 acts as a T cell suppressor and attenuates host antitumor immunity | NAT IMMUNOL | 尹玉新,北京大学,基础医学院,病理学系; | 5596.8 | 18 | 2020 | Overcoming cancer therapeutic bottleneck by drug repurposing | SIGNAL TRANSDUCT TAR | 崔永萍,山西医科大学,基础医学院,病理学; | 5166.88 | 19 | 2020 | Clinical and pathological investigation of patients with severe COVID20209 | JCI INSIGHT | 赵景民,解放军总医院第五医学中心,病理诊断与研究中心; | 5120.16 | 20 | 2020 | Targeting YAP1/LINC00152/FSCN1 Signaling Axis Prevents the Progression of Colorectal Cancer | ADV SCI | 马健,中南大学,基础医学院,肿瘤研究所; | 5088.64 | 21 | 2020 | mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges | CELL BIOSCI | 李红梅,广东医科大学; | 4868.8 | 22 | 2020 | Association of beta-blocker use with survival and pulmonary function in patients with chronic obstructive pulmonary and cardiovascular disease: a systematic review and meta-analysis | EUR HEART J | 向若兰,北京大学,,生理与病理生理学系; | 4686.24 | 23 | 2020 | Cryo-EM structures of inactive and active GABA(B) receptor | CELL RES | 张岩,浙江大学附属邵逸夫医院; | 4625.12 | 24 | 2020 | Triple-negative breast cancer molecular subtyping and treatment progress | BREAST CANCER RES | 余时沧,陆军军医大学,西南医院,病理学研究所; | 4509.6 | 25 | 2020 | MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration | AUTOPHAGY | 王建枝,华中科技大学,基础医学院病理生理学系; | 4486.72 | 26 | 2020 | Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors | MOL CELL | 张岩,浙江大学附属邵逸夫医院; | 4383.2 | 27 | 2020 | Hsa_circ_001680 affects the proliferation and migration of CRC and mediates its chemoresistance by regulating BMI1 through miR-340 | MOL CANCER | 丁彦青,南方医科大学,南方医院,病理科; | 4332.64 | 28 | 2020 | Role of PI3K/AKT pathway in cancer: the framework of malignant behavior | MOL BIOL REP | 彭娟,广州医科大学,附属第三医院,病理科; | 4308.64 | 29 | 2020 | The emerging roles of N6-methyladenosine (m6A) deregulation in liver carcinogenesis | MOL CANCER | Wong, Chun-Ming,香港大学; | 4204.64 | 30 | 2020 | Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer | CELL RES | 应建明,中国医学科学院,肿瘤医院,病理科; | 4113.12 | 31 | 2020 | Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets | CIRCULATION | 孙海鹏,上海交通大学,基础医学院,病生系; | 4096.48 | 32 | 2020 | CD4(+) T-Cell Endogenous Cystathionine gamma Lyase-Hydrogen Sulfide Attenuates Hypertension by Sulfhydrating Liver Kinase B1 to Promote T Regulatory Cell Differentiation and Proliferation | CIRCULATION | 徐国恒,北京大学,基础医学院,生理学与病理生理学系; | 4096.48 | 33 | 2020 | Transcriptional and proteomic insights into the host response in fatal COVID20209 cases | P NATL ACAD SCI USA | 王国平,华中科技大学,附属同济医院,病理科; | 4047.36 | 34 | 2020 | Circular RNA cESRP1 sensitises small cell lung cancer cells to chemotherapy by sponging miR-93-5p to inhibit TGF-beta signalling | CELL DEATH DIFFER | 郭琳琅,南方医科大学,珠江医院,病理科; | 4018.72 | 35 | 2020 | Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles | GUT | Leung, Suet Yi,香港大学; | 3939.04 | 36 | 2020 | Linc00173 promotes chemoresistance and progression of small cell lung cancer by sponging miR-218 to regulate Etk expression | ONCOGENE | 郭琳琅,南方医科大学,珠江医院,病理科; | 3865.44 | 37 | 2020 | Role of non-coding RNAs and RNA modifiers in cancer therapy resistance | MOL CANCER | 陶永光,中南大学,肿瘤研究所,病理; | 3820.64 | 38 | 2020 | The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB | AM J HUM GENET | LO, Yuk Ming Dennis，香港中文大学 | 3815.84 | 39 | 2020 | A novel pathway regulates social hierarchy via lncRNA AtLAS and postsynaptic synapsin IIb | CELL RES | 朱铃强,华中科技大学,基础医学院病理生理学系,; | 3793.12 | 40 | 2020 | Metal-organic frameworks-based nanozymes for combined cancer therapy | NANO TODAY | 田甘,陆军军医大学； | 3781.12 | 41 | 2020 | Accurate cancer cell identification and microRNA silencing induced therapy using tailored DNA tetrahedron nanostructures | CHEM SCI | 夏洪平,南京医科大学,基础医学院,; | 3704.96 | 42 | 2020 | The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression | MOL CANCER | 陶永光,中南大学,肿瘤研究所,病理; | 3692.64 | 43 | 2020 | Current understanding of metal ions in the pathogenesis of Alzheimer's disease | TRANSL NEURODEGENER | 王建枝,华中科技大学,基础医学院病理生理学系,; | 3691.52 | 44 | 2020 | Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression | GUT | 黄泽蕾,香港大学李嘉诚医学院,病理学系,; | 3683.04 | 45 | 2020 | Identification and validation of immune-related lncRNA prognostic signature for breast cancer | GENOMICS | 沈传陆,东南大学,医学院,病理学; | 3680.8 | 46 | 2020 | Germline genetic patterns underlying familial rheumatoid arthritis, systemic lupus erythematosus and primary Sjogren's syndrome highlight T cell-initiated autoimmunity | ANN RHEUM DIS | 张国红,汕头大学,,病理学与病理生理学; | 3664.32 | 47 | 2020 | A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor | CELL RES | 张岩,浙江大学附属邵逸夫医院 | 3601.12 | 48 | 2020 | Growth-Factor Free Multicomponent Nanocomposite Hydrogels That Stimulate Bone Formation | ADV FUNCT MATER | 孙宏晨,吉林大学,口腔医院,病理科; | 3589.76 | 49 | 2020 | Regulating tumor suppressor genes: post-translational modifications | SIGNAL TRANSDUCT TAR | 陶永光,中南大学,肿瘤研究所,病理; | 3566.88 | 50 | 2020 | Advances in targeted therapy for malignant lymphoma | SIGNAL TRANSDUCT TAR | 赵维莅,上海交通大学,瑞金医院,病理学; | 3438.88 | 51 | 2020 | Action mechanisms and research methods of tRNA-derived small RNAs | SIGNAL TRANSDUCT TAR | 郭俊明,宁波大学,临床医学,病理研究室; | 3438.88 | 52 | 2020 | Translational genomics of nasopharyngeal cancer | SEMIN CANCER BIOL | 罗国炜,香港中文大学,威尔斯亲王医院,病理解剖和细胞学系; | 3310.4 | 53 | 2020 | CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA20207 | MOL CANCER | 谢丹,中山大学,肿瘤防治中心,病理学; | 3308.64 | 54 | 2020 | Circular RNA circRHOBTB3 acts as a sponge for miR-654-3p inhibiting gastric cancer growth | J EXP CLIN CANC RES | 王爽,南方医科大学,南方医院,病理科; | 3298.72 | 55 | 2020 | SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID20209 | J HEPATOL | 赵景民,解放军总医院第五医学中心,,病理诊断与研究中心; | 3293.12 | 56 | 2020 | Pathological changes in the lungs and lymphatic organs of 12 COVID20209 autopsy cases | NATL SCI REV | 卞修武,陆军军医大学,西南医院,病理科; | 3246.88 | 57 | 2020 | Coupling of Integrin alpha 5 to Annexin A2 by Flow Drives Endothelial Activation | CIRC RES | 艾玎,天津医科大学,基础医学院,; | 3241.92 | 58 | 2020 | Molecular Classification of Breast Cancer | ADV ANAT PATHOL | 谢文杰,香港中文大学; | 3187.84 | 59 | 2020 | Ribosomal S6 protein kinase 4 promotes radioresistance in esophageal squamous cell carcinoma | J CLIN INVEST | 王哲,空军军医大学,西京医院,病理科; | 3154.4 | 60 | 2020 | Combining Allosteric and Orthosteric Drugs to Overcome Drug Resistance | TRENDS PHARMACOL SCI | 陆绍永,上海交通大学,基础医学院,病生系; | 3130.4 | 61 | 2020 | Tumor Necrosis Factor Receptor-Associated Factor 6 Promotes Hepatocarcinogenesis by Interacting With Histone Deacetylase 3 to Enhance c-Myc Gene Expression and Protein Stability | HEPATOLOGY | 李建明,中山大学,孙逸仙纪念医院,病理科; | 3099.36 | 62 | 2020 | Identification and characterization of extrachromosomal circular DNA in maternal plasma | P NATL ACAD SCI USA | LO, Yuk Ming Dennis ,香港中文大学; | 3087.36 | 63 | 2020 | Clinicopathological Features and Outcomes of Acute Kidney Injury in Critically Ill COVID20209 with Prolonged Disease Course: A Retrospective Cohort | J AM SOC NEPHROL | 王国平,华中科技大学,附属同济医院,病理科; | 3082.08 | 64 | 2020 | Pulmonary pathology of early-phase COVID20209 pneumonia in a patient with a benign lung lesion | HISTOPATHOLOGY | 袁静萍,武汉大学,人民医院,病理科; | 3028.96 | 65 | 2020 | Detection and characterization of jagged ends of double-stranded DNA in plasma | GENOME RES | 谢婷婷,香港中文大学,李嘉诚健康科学研究所,化学病理科; | 2980.8 | 66 | 2020 | HMGB1-associated necroptosis and Kupffer cells M1 polarization underlies remote liver injury induced by intestinal ischemia/reperfusion in rats | FASEB J | 柯尊富,中山大学,附属第一医院,病理科; | 2980.64 | 67 | 2020 | MCM family in gastrointestinal cancer and other malignancies: From functional characterization to clinical implication | BBA-REV CANCER | To, Ka Fai,香港中文大学; | 2963.2 | 68 | 2020 | Hypoxia-inducible factors and innate immunity in liver cancer | J CLIN INVEST | 黄泽蕾,香港大学李嘉诚医学院,病理学系,; | 2962.4 | 69 | 2020 | Inhibition of the ALDH18A1-MYCN positive feedback loop attenuates MYCN-amplified neuroblastoma growth | SCI TRANSL MED | 余时沧,陆军军医大学,西南医院,病理学研究所; | 2944 | 70 | 2020 | NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy | REDOX BIOL | 谭红梅,中山大学,中山医学院,病理生理科; | 2941.76 | 71 | 2020 | Acetaminophen sensitizing erastin-induced ferroptosis via modulation of Nrf2/heme oxygenase2020 signaling pathway in non-small-cell lung cancer | J CELL PHYSIOL | 李文通,潍坊医学院,基础医学院,病理学; | 2935.36 | 72 | 2020 | Intergenic Breakpoints Identified by DNA Sequencing Confound Targetable Kinase Fusion Detection in NSCLC | J THORAC ONCOL | 应建明,中国医学科学院,肿瘤医院,病理科; | 2905.12 | 73 | 2020 | Fatty Acid Oxidation Controls CD8(+) Tissue-Resident Memory T-cell Survival in Gastric Adenocarcinoma | CANCER IMMUNOL RES | 柯尊富,中山大学,附属第一医院,病理科; | 2878.08 | 74 | 2020 | Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect | NAT COMMUN | 王建枝,华中科技大学,基础医学院病理生理学系,; | 2872.48 | 75 | 2020 | Cooperative transport mechanism of human monocarboxylate transporter 2 | NAT COMMUN | 郭江涛,浙江大学 | 2872.48 | 76 | 2020 | The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR202025a-5p and miR202038-5p/4EBP2020 mediated cap-independent HIF2020 alpha translation | MOL CANCER | 李建明,中山大学,孙逸仙纪念医院,病理科; | 2860.64 | 77 | 2020 | Loss of GATA6 expression promotes lymphatic metastasis in bladder cancer | FASEB J | 范建兵,南方医科大学; | 2852.64 | 78 | 2020 | Molecular basis for assembly of the shieldin complex and its implications for NHEJ | NAT COMMUN | 尹玉新,北京大学,基础医学院,病理学系; | 2808.48 | 79 | 2020 | Clinically applicable histopathological diagnosis system for gastric cancer detection using deep learning | NAT COMMUN | 石怀银,中国人民解放军总医院,,病理科; | 2808.48 | 80 | 2020 | Self-Maintenance of Cardiac Resident Reparative Macrophages Attenuates Doxorubicin-Induced Cardiomyopathy Through the SR-A1-c-Myc Axis | CIRC RES | 陈骐,南京医科大学,基础医学院,病理生理学; | 2793.92 | 81 | 2020 | Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate IL-6-induced acute liver injury through miR-455-3p | STEM CELL RES THER | 石毓君,四川大学,华西医院,病理学系; | 2778.08 | 82 | 2020 | Single-cell transcriptome and antigen-immunoglobin analysis reveals the diversity of B cells in non-small cell lung cancer | GENOME BIOL | 武春燕,同济大学,上海市肺科医院,病理科; | 2756.48 | 83 | 2020 | Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy | NAT COMMUN | 张岩,浙江大学附属邵逸夫医院; | 2744.48 | 84 | 2020 | TrkB receptor cleavage by delta-secretase abolishes its phosphorylation of APP, aggravating Alzheimer's disease pathologies | MOL PSYCHIATR | 王小川,华中科技大学,基础医学院病理生理学系,; | 2731.2 | 85 | 2020 | VSMC-Specific Deletion of FAM3A Attenuated Ang II-Promoted Hypertension and Cardiovascular Hypertrophy | CIRC RES | 杨吉春,北京大学,基础医学院,生理与病生理系; | 2729.92 | 86 | 2020 | Nidogen 1-Enriched Extracellular Vesicles Facilitate Extrahepatic Metastasis of Liver Cancer by Activating Pulmonary Fibroblasts to Secrete Tumor Necrosis Factor Receptor 1 | ADV SCI | 任蕙苹,香港大学,医学院,病理学系; | 2720.64 | 87 | 2020 | Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells | ADV SCI | 黄金艳,上海交通大学,瑞金医院,上海血液学研究所病理学系; | 2720.64 | 88 | 2020 | Molecular subtyping in pancreatic neuroendocrine neoplasms: New insights into clinical, pathological unmet needs and challenges | BBA-REV CANCER | 陈杰,中国医学科学院,北京协和医院,病理科; | 2707.2 | 89 | 2020 | CARD9 promotes autophagy in cardiomyocytes in myocardial ischemia/reperfusion injury via interacting with Rubicon directly | BASIC RES CARDIOL | 蒋碧梅,中南大学,湘雅医学院,病理生理科; | 2684.96 | 90 | 2020 | Structural basis for activation of the growth hormone-releasing hormone receptor | NAT COMMUN | 张岩,浙江大学附属邵逸夫医院; | 2680.48 | 91 | 2020 | Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID20209 | PHARMACOL THERAPEUT | 柯尊富,中山大学,附属第一医院,病理科; | 2676.32 | 92 | 2020 | Placenta-derived extracellular vesicles induce preeclampsia in mouse models | HAEMATOLOGICA | 李敏,兰州大学; | 2670.4 | 93 | 2020 | Posterior Oropharyngeal Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | CLIN INFECT DIS | Lung, David Christopher,香港大学; | 2658.56 | 94 | 2020 | Cancer progression is mediated by proline catabolism in non-small cell lung cancer | ONCOGENE | 陶永光,中南大学,肿瘤研究所,病理; | 2649.44 | 95 | 2020 | Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer | MOL THER-NUCL ACIDS | 赵倩,上海交通大学,基础医学院,病生系; | 2597.12 | 96 | 2020 | HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis | FASEB J | 梁秀彬,南京医科大学,,病理生理学系; | 2596.64 | 97 | 2020 | Oncogenic State and Cell Identity Combinatorially Dictate the Susceptibility of Cells within Glioma Development Hierarchy to IGF1R Targeting | ADV SCI | 刘冲,浙江大学,神经科学研究所,病理学; | 2592.64 | 98 | 2020 | Breast cancer histopathological image classification using a hybrid deep neural network | METHODS | 饶晓松,北京大学病理学系; | 2580.32 | 99 | 2020 | Circulating tumor cells in cancer patients: developments and clinical applications for immunotherapy | MOL CANCER | 柯尊富,中山大学,附属第一医院,病理科; | 2540.64 | 100 | 2020 | C/EBP beta is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer's disease | MOL PSYCHIATR | 王小川,华中科技大学,基础医学院病理生理学系,; | 2539.2 |
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