邵旭升:博士,副教授,硕士生导师。2009年7月毕业于华东理工大学应用化学专业,导师李忠教授,主要从事新烟碱杀虫剂的创制研究。2009年7月应聘为华东理工大学讲师,2012年9月应聘为副教授,硕士研究生导师。2012年7月至2013年7月在美国加州大学伯克利分校(University of California at Berkeley)John E. Casida教授课题组从事农药的毒理、代谢和作用机制研究。目前主要从事新农药创制的相关研究,发表论文30余篇,申请专利20多项。作为项目负责人承担了国家自然科学基金,上海市教育委员会科研创新项目,上海市自然科学基金,澳大利亚DC研究基金,中央高校基本科研业务费等项目,并作为项目主要研究人员参与国家863项目和十二五国家科技支撑计划项目。 发表论文 -------------------------------------------------------------------- 1. Jingwei Zhang, Xusheng Shao*, Zhong Li, Xiaoyong Xu*. Bis-phenylazoneonicotinoids as Divalent Insecticides: Design, Synthesis and Activity. Letters in Drug Design & Discovery 2013, DOI: 10.2174/15701808113109990049. 2. Liping Ren, Yanpeng Lou, Nanyang Chen, Shanshan Xia, Xusheng Shao*, Xiaoyong Xu*, Zhong Li. Synthesis and Insecticidal Activities of Tetrahydroimidazo[1,2-a]pyridinones: Further Exploration on cis-Neonicotinoids. Synthetic Commun. 2013, in press. 3. Xusheng Shao*, Shanshan Xia, Kathleen A. Durkin, John E. Casida*. Insect Nicotinic Receptor Interactions in Vivo with Neonicotinoid, Organophosphorus and Methylcarbamate Insecticides and a Synergist. Proc. Natl. Acad. Sci. U.S.A. 2013, DOI: 10.1073/pnas.1316369110. 4. Xusheng Shao, Tami L. Swenson, John E. Casida*. Cycloxaprid Insecticide: Nicotinic Acetylcholine Receptor Binding Site and Metabolism. J. Agric. Food Chem. 2013, 61, 7883–7888. 5. Xusheng Shao, Zewen Liu, Xiaoyong Xu, Zhong Li*, Xuhong Qian. Overall Status of Neonicotinoid Insecticides in China: Production, Application and Innovation. J. Pestic. Sci. 2013, 38, 1–9. 6. Yinbo Chen, Jiling Li, Xusheng Shao, Xiaoyong Xu, Zhong Li*. Design, synthesis and insecticidal activity of novel anthranilic diamides with benzyl sulfide scaffold. Chin. Chem. Lett. 2013, 24, 673–676. 7. Zhenjun Ye, Lina Shi, Xusheng Shao, Xiaoyong Xu, Zhiping Xu, Zhong Li*. Pyrrole- and Dihydropyrrole-Fused Neonicotinoids: Design, Synthesis, and Insecticidal Evaluation. J. Agric. Food Chem. 2013, 61, 312–319. 8. Xusheng Shao*, Xinglong Huang, Qian Shi, Zhong Li, Liming Tao, Gonghua Song*. Synthesis and Insecticidal Activities of Chlorothiazolyl Analogues of Nitromethylene Neonicotinoids with Tetrahydropyridine Fixed cis-Configuration. J. Heterocycl. Chem. 2012, 49, 1136–1142. 9. Siyuan Lu, Xusheng Shao, Zhong Li, Zhiping Xu, Shishuai Zhao, Yingli Wu, Xiaoyong Xu*. Design, Synthesis and Particular Biological Behaviors of Chain-opening Nitromethylene Neonicotinoids with cis-Configuration. J. Agric. Food Chem. 2012, 60, 322–330. 10. Baozhu Wang, Jiagao Cheng, Zhiping Xu, Xiaoyong Xu, Xusheng Shao and Zhong Li*. Synthesis and Biological Activity Evaluation of Novelβ-Substituted Nitromethylene Neonicotinoid Analogues. Molecules 2012, 17, 10014–10025. 11. Baozhu Wang, Xiaoyong Xu, Jiagao Cheng, Xusheng Shao and Zhong Li*. Supramolecular Water Morphology and Methanol Solvate in a Functionalized Pymetrozine Host. Asian Journal of Chemistry 2012, 24, 2541–2545. 12. Xusheng Shao, Zhenjun Ye, Haibo Bao, Zewen Liu, Xiaoyong Xu, Zhong Li*, Xuhong Qian*. Advanced research on cis-neonicotinoids. Chimia 2011, 65, 957–960. 13. Zhenjun Ye, Shuang Xia, Xusheng Shao, Jiagao Cheng, Xiaoyong Xu, Zhiping Xu, Zhong Li*, Xuhong Qian*. Design Synthesis, Crystal Structure Analysis, and Insecticidal Evaluation of Phenylazoneonicotinoids. J. Agric. Food Chem. 2011, 59, 10615–10623. 14. Xusheng Shao, Hanyan Liu, Haibo Bao, Xiaoyong Xu, Zewen Liu, Zhong Li*. The Mode of Action of a Nitroconjugated Neonicotinoid and the Effects of Target Site Mutation Y151S on its Potency. Insect Biochem. Mol. Biol. (Insect Biochemistry and Molecular Biology), 2011, 41, 440–445. 15. Xusheng Shao, Philip W. Lee, Xiaoyong Xu, Zewen Liu, Zhong Li*, Xuhong Qian. cis-Configuration: A New Tactic/Rationale for Neonicotinoid Molecular Design. J. Agric. Food Chem. 2011, 59, 2943–2949. 16. Zhenjun Ye, Renbo Xu, Xusheng Shao, Xiaoyong Xu, Zhong Li*. One-pot synthesis of polyfunctionalized 4H-pyran derivatives bearing fluorochloro pyridyl moiety. Tetrahedron Lett. 2010, 51, 4991–4994. 17. Xusheng Shao, Hua Fu, Xiaoyong Xu, Xinglei Xu, Zhong Li*, Zewen Liu. Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid: Design, Synthesis, Crystal Structure and Insecticidal Activities. J. Agric. Food Chem. 2010, 58, 2696–2702. 18. Xusheng Shao, Zhiping Xu, Xianfeng Zhao, Xiaoyong Xu, Liming Tao, Zhong Li*, Xuhong Qian*. Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. J. Agric. Food Chem. 2010, 58, 2690–2695. 19. Xusheng Shao, Xiaoyong Xu, Zhong Li *, Xuhong Qian*. Design, Synthesis and Insecticidal Activities of Novel Analogues of Neonicotinoids: Replacement of Nitromethylene with Nitro-Conjugated System. J. Agric. Food Chem. 2009, 57, 951–957. 20. Xusheng Shao, Wenwen Zhang, Yanqing Peng, Zhong Li*. cis-Nitromethylene Neonicotinoids as new nicotinic family: Sythesis,structural diersity, and insecticidal evaluation of hexahydroimidazo[1,2-a]pyridine. Bioorg. Med. Chem. Lett. 2008, 18, 6513–6516. 21. Xiaoyong Xu, Haibo Bao, Xusheng Shao, Yixi Zhang, Xiangmei Yao, Zewen Liu*, Zhong Li*. Pharmacological of cis-ntromethylene neonicotinoids: overlapping one binding site of imidacloprid in the brown planthopper, Nilaparvata lugens. Insect Molec. Biol. 2010, 19, 1–8. 22. Li Cui, Lina Sun, Xusheng Shao, Yazhong Cao, Daibin Yang, Zhong Li*, Huizhu Yuan*. Systemic action of novel neonicotinoid insecticide IPP-10 and its effect on the feeding behaviour of Rhopalosiphum padi on wheat. Pest Manag. Sci. 2010, 66, 779–785. 23. Xianfeng Zhao, Xusheng Shao, Zhuyan Zou, Xiaoyong Xu*. Photodegradation of Novel Nitromethylene Neonicotinoids with Tetrahydropyridine-Fixed cis Configuration in Aqueous Solution. J. Agric. Food Chem. 2010, 58, 2746–2754. 24. Zhongzhen Tian, Xusheng Shao, Zhong Li*, Xuhong Qian*. Synthesis, Insecticidal Activity, and QSAR of Novel Nitromethylene Neonicotinoids with Tetrahydropyridine Fixed cis Configuration and Exo-Ring Ether Modification. J. Agric. Food Chem. 2007, 55, 2288–2292. 25. Mingyi Cai, Zhong Li, Feng Fan, Qingchun Huang, Xusheng Shao, Gonghua Song*. Design and Synthesis of Novel Insecticides Based on Serotonergic Ligand PAPP. J. Agric. Food Chem. 2010, 58, 2624–2629.