Effect of Flow Baffles on the Dialysate Flow Distribution of Hollow-Fiber Hemodialyzers: A Nonintrusive Experimental Study Using MRI-Reference-Cited by-同舟云学术

Effect of Flow Baffles on the Dialysate Flow Distribution of Hollow-Fiber Hemodialyzers: A Nonintrusive Experimental Study Using MRI

Published:2003-08-01 Issue:4 Volume:125 Page:481-489
ISSN:0148-0731
Container-title:Journal of Biomechanical Engineering
language:en
Short-container-title:

Author:

Poh Churn K.¹,Hardy Peter A.²,Liao Zhijie¹,Huang Zhongping¹,Clark William R.³,Gao Dayong¹⁴

Affiliation:

1. Department of Mechanical Engineering, University of Kentucky, Lexington, KY

2. Center for Biomedical Engineering, University of Kentucky, Lexington, KY

3. Rental Division, Baxter Healthcare Corporation, McGaw Park, IL

4. and Center for Biomedical Engineering, University of Kentucky, Lexington, KY

Abstract

We used an innovative, nonintrusive MRI technique called the two-dimensional (2D) Phase-Contrast (2DPC) velocity-imaging technique to investigate the effect of flow baffles on the dialysate-side flow distribution in two different hollow-fiber hemodialyzers (A and B); each with flow rates between 200 and 1000 mL/min (3.33×10−6 and 1.67×10−5 m3/s). Our experimental results show that (1) the dialysate-side flow distribution was nonuniform with channeling flow occurred at the peripheral cross section of these hollow-fiber hemodialyzers, and (2) the existing designs of flow baffles failed to promote uniform dialysate-side flow distribution for all flow rates studies.

Publisher

ASME International

Subject

Physiology (medical),Biomedical Engineering

Link

http://asmedigitalcollection.asme.org/biomechanical/article-pdf/125/4/481/5657997/481_1.pdf

Reference32 articles.

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