Effect of a Lipid Pool on Stress/Strain Distributions in Stenotic Arteries: 3-D Fluid-Structure Interactions (FSI) Models
Author:
Tang Dalin1, Yang Chun2, Kobayashi Shunichi3, Ku David N.4
Affiliation:
1. Mathematical Sciences Department, Worcester Polytechnic Institute, Worcester, MA 01609 2. Mathematics Dept, Beijing Normal University, China 3. Dept. of Functional Machinery and Mechanics, Shinshu Univ., Nagano, Japan 4. School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332
Abstract
Nonlinear 3-D models with fluid-structure interactions (FSI) based on in vitro experiments are introduced and solved by ADINA to perform flow and stress/strain analysis for stenotic arteries with lipid cores. Navier-Stokes equations are used as the governing equations for the fluid. Hyperelastic Mooney-Rivlin models are used for both the arteries and lipid cores. Our results indicate that critical plaque stress/strain conditions are affected considerably by stenosis severity, eccentricity, lipid pool size, shape and position, plaque cap thickness, axial stretch, pressure, and fluid-structure interactions, and may be used for possible plaque rupture predictions.
Publisher
ASME International
Subject
Physiology (medical),Biomedical Engineering
Reference40 articles.
1. Burke, A. P., Farb, A., Malcom, G. T., Liang, Y. H., Smialek, J. E., and Virmani, R., 1999, “Plaque Rupture and Sudden Death Related to Exertion in Men With Coronary Artery Disease,” J. Am. Med. Assoc., 281(10), pp. 921–926. 2. Fuster, V., Stein, B., Ambrose, J. A., Badimon, L., Badimon, J. J., and Chesebro, J. H., 1990, “Atherosclerotic Plaque Rupture and Thrombosis,” Circulation, Supplement II,82(3), pp. II-47–II-59II-47–II-59. 3. Davies, M. J., and Thomas, A. C., 1985, “Plaque Fissuring-the Cause of Acute Myocardial Infarction, Sudden Ischemic Death, and Crecendo Angina,” Br. Heart J., 53, pp. 363–373. 4. Falk, E., Shah, P. K., and Fuster, V., 1995, “Coronary Plaque Disruption,” Circulation, 92, pp. 657–671. 5. Ravn, H. B., and Falk, E., 1995, “Histopathology of Plaque Rupture,” Cardiol. Clin., 17, pp. 263–270.
Cited by
101 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|