Where to now? AVERT answered an important question, but raised many more-Reference-Cited by-同舟云学术

Where to now? AVERT answered an important question, but raised many more

Published:2017-08-18 Issue:7 Volume:12 Page:683-686
ISSN:1747-4930
Container-title:International Journal of Stroke
language:en
Short-container-title:International Journal of Stroke

Author:

Bayley Mark T¹²^ORCID,Bowen Audrey³,English Coralie⁴,Teasell Robert⁵,Eng Janice J⁶

Affiliation:

1. Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Toronto, Toronto, Canada

2. Toronto Rehabilitation Institute-University Health Network, Toronto, Canada

3. Division of Neuroscience and Experimental Psychology, University of Manchester MAHSC, Manchester, UK

4. School of Health Sciences and Priority Research Centre for Stroke and Brain Injury, Hunter Medical Research Institute, University of Newcastle, Callaghan, Australia

5. Lawson Health Research Institute, Western University, London, Canada

6. Department of Physical Therapy, University of British Columbia and GF Strong Rehab Centre, Vancouver, Canada

Abstract

A Very Early Rehabilitation Trial (AVERT) was a Phase 3 randomized trial with over 2100 subjects post stroke that had unexpected results with better outcomes for usual care than those receiving very early mobilization. This review of published stroke clinical practice guidelines highlights that recommendations for mobilization have changed after publication of AVERT but also that developers have struggled to provide recommendations for appropriate dose, duration and intensity of mobilization in the acute post stroke period with available analyses from AVERT and other literature. This review highlights the priority research questions about early rehabilitation post stroke that need to be addressed through future large scale randomized controlled trials.

Publisher

SAGE Publications

Subject

Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1747493017727338

Reference15 articles.

1. Could upright posture be harmful in the early stages of stroke? – Author's reply

2. Early exercise training improves ischemic outcome in rats by cerebral hemodynamics

3. The effects of early exercise on brain damage and recovery after focal cerebral infarction in rats

4. Early treadmill training promotes motor function after hemorrhagic stroke in rats

5. Physical Activity Early after Stroke and Its Association to Functional Outcome 3 Months Later

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