Individual Differences in Response to Supervised Exercise Therapy for Peripheral Artery Disease

Author:

Whipple Mary O.12ORCID,Schorr Erica N.2,Talley Kristine M.C.2,Wolfson Julian3,Lindquist Ruth2,Bronas Ulf G.4,Treat-Jacobson Diane2

Affiliation:

1. Divisions of Geriatric Medicine and General Internal Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

2. School of Nursing, University of Minnesota – Twin Cities, Minneapolis, MN, USA

3. Division of Biostatistics, School of Public Health, University of Minnesota – Twin Cities, Minneapolis, MN, USA

4. Department of Biobehavioral Health Science, College of Nursing, University of Illinois – Chicago, Chicago, IL, USA

Abstract

Nonresponse to exercise has been extensively examined in young athletes but is seldom reported in studies of aerobic exercise interventions in older adults. This study examined the prevalence of nonresponse and poor response to exercise in functional and quality of life outcomes and response patterns between and among older adults undergoing 12-weeks of supervised exercise therapy for the management of peripheral artery disease ( N = 44, mean age 72.3 years, 47.7% female). The prevalence of nonresponse (no change/decline in performance) in walking distance was 31.8%. The prevalence of poor response (lack of a clinically meaningful improvement) was 43.2%. Similar patterns of response were observed in both objective and patient-reported measures of physical function. All participants improved in at least one outcome; only two participants improved in all measured outcomes. Additional research should examine modifiable predictors of response to inform programming and maximize an individual’s potential benefit from exercise therapy.

Funder

National Center for Advancing Translational Sciences

National Hartford Center of Gerontological Nursing Excellence

national institute on aging

Midwest Nursing Research Society

National Institute of Nursing Research

Publisher

SAGE Publications

Subject

General Nursing

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