Impact of traumatic life events on clinical variables of individuals with first-episode psychosis and healthy controls

Author:

Butjosa Anna123,Usall Judith12,Vila-Badia Regina12ORCID,Mezquida Gisela34,Cuesta Manuel J56,Rodríguez-Toscano Elisa78,Amoretti Silvia34,Lobo Antonio3910ORCID,González-Pinto Ana311,Espliego Ana8,Corripio Iluminada312,Vieta Eduard313,Baeza Inmaculada314,Bergé Dani31516,Bernardo Miguel34ORCID,Bioque Miquel,García-Rizo Clemente,Mayoral María,Merchan Jessica,Alonso-Solís Anna,Rabella Mireia,López Purificación,Zorrilla Iñaki,De-la-Cámara Concepción,Barcones Fe,Sanjuan Julio,Dolores Moltó Mª,Morro Laura,Monserrat Clara,Verdolini Norma,Salagre Estela,la Serna Elena de,Castro-Fornieles Josefina,Contreras Fernández Fernando,Saiz Masvidal Cristina,Paz Garcia-Portilla Maria,Bousoño Manuel,Gutiérrez Fraile Miguel,Zabala Rabadán Arantzazu,Dompablo Mónica,Rodriguez-Jimenez Roberto,Rubio-Abadal Elena,Pardo Marta,Sarró Salvador,Pomarol-Clotet Edith,Ibanez Angela,Sánchez-Torres Ana M.,Selva-Vera Gabriel

Affiliation:

1. Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain

2. Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain

3. Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Spain

4. Barcelona Clinic Schizophrenia Unit, Hospital Clinic of Barcelona, Neuroscience Institute, University of Barcelona, IDIBAPS, Spain

5. Department of Psychiatry, Complejo Hospitalario de Navarra, Pamplona, Spain

6. Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain

7. Instituto de Psiquiatría y Salud Mental del Hospital Gregorio Marañón, Servicio de Psiquiatría del Niño y del Adolescente, Madrid, Spain

8. Departamento de Psicología experimental, Procesos psicológicos y logopedia, Universidad Complutense de Madrid, Spain

9. Department of Medicine and Psychiatry, University of Zaragoza, Spain

10. Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain

11. Department of Psychiatry, Hospital Universitario de Alava, BIOARABA, UPV/EHU, Vitoria, Spain

12. Department of Psychiatry, Hospital de Sant Pau, Barcelona, Spain

13. Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, Catalonia, Spain

14. Child and Adolescent Psychiatry and Psychology Department, SGR489, Hospital Clinic of Barcelona, Institute of Neurosciences, University of Barcelona, Spain

15. Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain

16. Autonomous University of Barcelona (UAB), Cerdanyola del Vallès, Spain

Abstract

Background: Traumatic life events (TLEs) are one of the most robust environmental risk factors for the onset of first-episode psychosis (FEP). Aims: To explore TLEs in FEP patients and healthy controls (HC), to analyze gender differences and to examine whether TLEs were associated with sociodemographic, clinical and psychofunctional variables in all FEP sample and split by age. Methods: Descriptive and cross-sectional study. Three hundred and thirty-five FEP and 253 HC were recruited at 16 Spanish mental health research centers. The Traumatic Experiences in Psychiatric Outpatients Questionnaire was administered. Results: We found a higher number of TLEs in FEP than in HC, and the proportion of individuals with three or more TLEs was significantly higher in the FEP group. No differences were found in terms of gender and age. There was no relationship between total number of TLEs and psychotic symptomatology and functional outcomes. Conclusions: The number and cumulative TLEs should be taken into account in the detection, epidemiology and process of recovery in FEP.

Funder

Ministerio de Economia y Competitividad

Instituto de Salud Carlos III, Fondo Europeo de Desarrollo Regional, Union Europea, Una Manera de Hacer Europa

Centro de Investigacion Biomedica en Red de Salud Mental, CIBERSAM, by the CERCA Programme / Generalitat de Catalunya and Secretaria d’ Universitats I Recerca del Departament d’Economia I Coneixement

Publisher

SAGE Publications

Subject

Psychiatry and Mental health

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