Metabolic Syndrome Exacerbating Ankle-Brachial Index in Asian Type 2 Diabetic Patients

Author:

Lee I-Te1,Lee Wen-Jane2,Sheu Wayne Huey-Herng3

Affiliation:

1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, School of Medicine, Chung Shan Medical University, Taichung, Taiwan, School of Medicine, National Yang-Ming University, Taipei, Taiwan

2. Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan

3. Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, School of Medicine, Chung Shan Medical University, Taichung, Taiwan, School of Medicine, National Yang-Ming University, Taipei, Taiwan, Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan,

Abstract

The aim was to assess the association between metabolic syndrome (MetS) and ankle-brachial index (ABI) in Asians with or without diabetes. In this cross-sectional study, the components of MetS, lipid profiles, and ABI were assessed. A total 441 participants were enrolled, and the ABI was significantly lower (1.09 ± 0.10 vs 1.12 ± 0.13, P = .015) in participants with MetS (n = 269) as compared with those without MetS (n = 172). To dissect the influence of diabetes, these 2 groups were further categorized according to either diabetes or not. Ankle-brachial index was highest in participants with neither MetS nor diabetes and lowest in those with both MetS and diabetes (P value for trend <.001). Metabolic syndrome is also an independent risk factor for low ABI in participants with diabetes (P = .018). Thus, MetS is usually associated with lower ABI, most obvious in diabetic participants.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

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