Arsenic exposure and non-carcinogenic health effects-Reference-Cited by-同舟云学术

Arsenic exposure and non-carcinogenic health effects

Published:2021-10-05 Issue:12_suppl Volume:40 Page:S826-S850
ISSN:0960-3271
Container-title:Human & Experimental Toxicology
language:en
Short-container-title:Hum Exp Toxicol

Author:

Martínez-Castillo Macario¹^ORCID,García-Montalvo Eliud A²,Arellano-Mendoza Mónica G³,Sánchez-Peña Luz del C⁴,Soria Jasso Luis E⁵,Izquierdo-Vega Jeannett A⁶,Valenzuela Olga L²,Hernández-Zavala Araceli¹^ORCID

Affiliation:

1. Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México, México

2. Facultad de Ciencias Químicas, Universidad Veracruzana, Orizaba, México

3. Laboratorio de Investigación en Enfermedades Crónico-Degenerativas, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México, México

4. Departamento de Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de Mexico, México

5. Centro de Investigación en Biología de la Reproducción, Área Académica de Medicina del Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Pachuca, México

6. Área Académica de Medicina, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Pachuca, México

Abstract

Inorganic arsenic (iAs) exposure is a serious health problem that affects more than 140 million individuals worldwide, mainly, through contaminated drinking water. Acute iAs poisoning produces several symptoms such as nausea, vomiting, abdominal pain, and severe diarrhea, whereas prolonged iAs exposure increased the risk of several malignant disorders such as lung, urinary tract, and skin tumors. Another sensitive endpoint less described of chronic iAs exposure are the non-malignant health effects in hepatic, endocrine, renal, neurological, hematological, immune, and cardiovascular systems. The present review outlines epidemiology evidence and possible molecular mechanisms associated with iAs-toxicity in several non-carcinogenic disorders.

Funder

Secretaría de Investigación y Posgrado, Instituto Politécnico Nacional

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/09603271211045955

Reference296 articles.

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