Levetiracetam pharmacokinetics in venovenous extracorporeal membrane oxygenation: A case report-Reference-Cited by-同舟云学术

Levetiracetam pharmacokinetics in venovenous extracorporeal membrane oxygenation: A case report

Published:2024-07-25 Issue: Volume: Page:
ISSN:0267-6591
Container-title:Perfusion
language:en
Short-container-title:Perfusion

Author:

Solomon Diana¹^ORCID,Gaines Devon²,Peterson Lars-Kristofer²³⁴

Affiliation:

1. Department of Pharmacy, Cooper University Healthcare, Camden, NJ, USA

2. Division of Critical Care Medicine, Cooper University Healthcare, Camden, NJ, USA

3. Departments of Medicine and Emergency Medicine, Cooper University Healthcare, Camden, NJ, USA

4. Cooper Medical School of Rowan University, Camden, NJ, USA

Abstract

This case report describes the pharmacokinetics of levetiracetam in a critically ill patient supported on venovenous membrane oxygenation. While levetiracetam has emerged as a first line option to treat seizures in critically ill patients, there is limited information available regarding the impact of extracorporeal membrane oxygenation on the pharmacokinetics of this medication. This report contributes to the limited body of literature describing the pharmacokinetics of medications in extracorporeal membrane oxygenation.

Publisher

SAGE Publications

Link

https://journals.sagepub.com/doi/pdf/10.1177/02676591241268422

Reference18 articles.

1. Guidelines for the Evaluation and Management of Status Epilepticus

2. Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults: Report of the Guideline Committee of the American Epilepsy Society

3. Safety and Efficacy of Levetiracetam for Critically Ill Patients with Seizures

4. A Narrative Review of the Impact of Extracorporeal Membrane Oxygenation on the Pharmacokinetics and Pharmacodynamics of Critical Care Therapies