Radiomics in prostate cancer: an up-to-date review

Author:

Ferro Matteo1ORCID,de Cobelli Ottavio2,Musi Gennaro2,del Giudice Francesco3,Carrieri Giuseppe4,Busetto Gian Maria4ORCID,Falagario Ugo Giovanni4,Sciarra Alessandro3,Maggi Martina3,Crocetto Felice5,Barone Biagio5ORCID,Caputo Vincenzo Francesco5ORCID,Marchioni Michele67,Lucarelli Giuseppe8,Imbimbo Ciro5,Mistretta Francesco Alessandro910,Luzzago Stefano910,Vartolomei Mihai Dorin1112,Cormio Luigi1314,Autorino Riccardo15ORCID,Tătaru Octavian Sabin16

Affiliation:

1. Department of Urology, European Institute of Oncology, IRCCS, Milan, Italy, via Ripamonti 435 Milano, Italy

2. Department of Urology, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hematology-Oncology, Università degli Studi di Milano, Milan, Italy

3. Department of Urology, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy

4. Department of Urology and Organ Transplantation, University of Foggia, Foggia, Italy

5. Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples ‘Federico II’, Naples, Italy

6. Department of Medical, Oral and Biotechnological Sciences, G. d’Annunzio, University of Chieti, Chieti, Italy; Urology Unit, ‘SS. Annunziata’ Hospital, Chieti, Italy

7. Department of Urology, ASL Abruzzo 2, Chieti, Italy

8. Department of Emergency and Organ Transplantation, Urology, Andrology and Kidney Transplantation Unit, University of Bari, Bari, Italy

9. Department of Urology, European Institute of Oncology, IRCCS, Milan, Italy

10. Università degli Studi di Milano, Milan, Italy

11. Department of Cell and Molecular Biology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mures, Târgu Mures, Romania

12. Department of Urology, Medical University of Vienna, Vienna, Austria

13. Urology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy

14. Urology Unit, Bonomo Teaching Hospital, Foggia, Italy

15. Division of Urology, VCU Health, Richmond, VA, USA

16. Institution Organizing University Doctoral Studies, I.O.S.U.D., George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mures, Târgu Mures, Romania

Abstract

Prostate cancer (PCa) is the most common worldwide diagnosed malignancy in male population. The diagnosis, the identification of aggressive disease, and the post-treatment follow-up needs a more comprehensive and holistic approach. Radiomics is the extraction and interpretation of images phenotypes in a quantitative manner. Radiomics may give an advantage through advancements in imaging modalities and through the potential power of artificial intelligence techniques by translating those features into clinical outcome prediction. This article gives an overview on the current evidence of methodology and reviews the available literature on radiomics in PCa patients, highlighting its potential for personalized treatment and future applications.

Publisher

SAGE Publications

Subject

Urology

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