Signal Transduction Mechanisms in Mesenchymal Cells-Reference-Cited by-同舟云学术

Signal Transduction Mechanisms in Mesenchymal Cells

Published:1994-09 Issue:3 Volume:5 Page:291-310
ISSN:1045-4411
Container-title:Critical Reviews in Oral Biology & Medicine
language:en
Short-container-title:Critical Reviews in Oral Biology & Medicine

Author:

McAllister Bradley S.¹,Walters John D.²,Olson Merle S.³

Affiliation:

1. Departments of Periodontology and Oral Molecular Biology, Oregon Health Sciences University, 611 SW Campus Drive, Portland, OR 97201-3097

2. Department of Periodontology and Medical Biochemistry, The Ohio State University Health Sciences Center, Columbus, OH 43210

3. Department of Biochemistry, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284

Abstract

Mesenchymal cells are continually stimulated by a wide spectrum of biological mediators. These mediators bind to receptors on the cell surface and initiate a cascade of signaling events. The initial signal transduction pathways known to be stimulated in mesenchymal cells include phospholipase C, phospholipase D, phospholipase A2, adenylate cyclase, receptor tyrosine kinases, and receptor serine/threonine kinases. These pathways are reviewed and specific applications for therapeutic intervention in wound healing and regenerative therapy in the periodontium are discussed.

Publisher

SAGE Publications

Subject

General Dentistry,Otorhinolaryngology

Link

http://journals.sagepub.com/doi/pdf/10.1177/10454411940050030501

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