Primary small gauge pars plana vitrectomy and silicone oil endotamponade for endophthalmitis after cataract surgery: Clinical and OCT findings

Author:

Fiore Tito1ORCID,Lupidi Marco1ORCID,Cerquaglia Alessio1,Giansanti Fabrizio2,Reibaldi Michele3ORCID,Iaccheri Barbara1ORCID,Tucci Davide1ORCID,Messina Marco1,Cagini Carlo1ORCID

Affiliation:

1. Department of Biomedical and Surgical Sciences, Section of Ophthalmology, University of Perugia, S. Maria della Misericordia Hospital, Perugia, Italy

2. Department of Translational Surgery and Medicine, Ophthalmology Unit, University of Firenze, Firenze, Italy

3. Department of Ophthalmology, University of Turin, Turin, Italy

Abstract

Background Retrospective analysis of morphological and functional outcomes after pars-plana vitrectomy and Silicone-Oil (SO) endotamponade in acute postoperative endophthalmitis (APOE). Methods Minimum follow-up was 6 months. Every included patient received best-corrected visual acuity (BCVA) assessment, pre-operatively and at last follow-up. Spectralis OCT was used to investigate disorganization of inner (DRIL) and outer (DROL) retinal layers at 1, 3, 6 months and at last follow-up. OCT-A was performed to assess foveal avascular zone (FAZ) and vascular perfusion density (VPD) at 6 months and at last follow-up. Results Seventeen eyes were recruited. Postoperative findings: BCVA ≥ 20/40 (in 14 eyes); epiretinal membranes (13); hyperreflective epiretinal material soon after surgery in (6) SO-filled eyes; inner retinal layers atrophy (5); macular edema (2); DROL (4) with persistent EZ disruption at final visit (2); no significant difference between study and fellow eyes in central macular thickness, FAZ and VPD; VPD decreased in all cases with prominent disorganization of retinal architecture. Conclusion OCT changes after APOE can be persistent or completely/partially self-resolving and seems related to the outward progression path of the infection/inflammation from the vitreous cavity to the inner and outer retina, rather than to the surgery.

Publisher

SAGE Publications

Subject

Ophthalmology,General Medicine

Reference31 articles.

1. Postoperative Endophthalmitis

2. Results of the Endophthalmitis Vitrectomy Study: A Randomized Trial of Immediate Vitrectomy and of Intravenous Antibiotics for the Treatment of Postoperative Bacterial Endophthalmitis. Arch. Ophthalmol 1995.

3. Vitrectomy for Endophthalmitis

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