Imaging of left heart intracardiac thrombus: clinical needs, current imaging, and emerging cardiac magnetic resonance techniques

Author:

Chang Peng12,Xiao Jiayu3ORCID,Hu Zhehao34,Kwan Alan C.5,Fan Zhaoyang678

Affiliation:

1. Biomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA

2. Department of Cardiovascular, Lanzhou University Second Hospital, Lanzhou, China

3. Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

4. Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA

5. Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

6. Department of Radiology, Keck School of Medicine, University of Southern California, 2250 Alcazar Street, CSC Room 104, Los Angeles, CA 90033, USA

7. Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

8. Department of Biomedical Engineering, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

Abstract

Intracardiac thrombus in the left atrium and atrial appendage (LA/LAA) and left ventricle (LV) increases the risk of systemic thromboembolism and causes potentially devastating diseases such as ischemic stroke and acute ischemia in abdominal organs and lower extremities. Detecting the presence and monitoring the resolution of left heart intracardiac thrombus are of vital importance for stratifying patients and guiding treatment decisions. Currently, echocardiography is the most frequently used method for the above clinical needs, followed by computed tomography. An increasing number of studies have been performed to investigate the value of cardiac magnetic resonance (CMR) as an alternative imaging modality given its several unique strengths. This article provides an overview of the clinical relevance of the LA/LAA and LV thrombus as well as the diagnostic performance of the current imaging modalities and emerging CMR techniques.

Funder

Cuiying Science and Technology Innovation Project

Publisher

SAGE Publications

Subject

Pharmacology (medical),Cardiology and Cardiovascular Medicine

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