Application of Deep Learning in Cancer Prognosis Prediction Model

Author:

Zhang Heng1234ORCID,Xi Qianyi12345ORCID,Zhang Fan12345,Li Qixuan12345,Jiao Zhuqing5,Ni Xinye1234

Affiliation:

1. Department of Radiotherapy Oncology, Changzhou No.2 People's Hospital, Nanjing Medical University, Changzhou, China

2. Jiangsu Province Engineering Research Center of Medical Physics, Changzhou, China

3. Medical Physics Research Center, Nanjing Medical University, Changzhou, China

4. Key Laboratory of Medical Physics in Changzhou, Changzhou, China

5. School of Microelectronics and Control Engineering, Changzhou University, Changzhou, China

Abstract

As an important branch of artificial intelligence and machine learning, deep learning (DL) has been widely used in various aspects of cancer auxiliary diagnosis, among which cancer prognosis is the most important part. High-accuracy cancer prognosis is beneficial to the clinical management of patients with cancer. Compared with other methods, DL models can significantly improve the accuracy of prediction. Therefore, this article is a systematic review of the latest research on DL in cancer prognosis prediction. First, the data type, construction process, and performance evaluation index of the DL model are introduced in detail. Then, the current mainstream baseline DL cancer prognosis prediction models, namely, deep neural networks, convolutional neural networks, deep belief networks, deep residual networks, and vision transformers, including network architectures, the latest application in cancer prognosis, and their respective characteristics, are discussed. Next, some key factors that affect the predictive performance of the model and common performance enhancement techniques are listed. Finally, the limitations of the DL cancer prognosis prediction model in clinical practice are summarized, and the future research direction is prospected. This article could provide relevant researchers with a comprehensive understanding of DL cancer prognostic models and is expected to promote the research progress of cancer prognosis prediction.

Funder

Jiangsu Provincial Medical Key Discipline Construction Unit (Oncology Therapeutics

Social Development Project of Jiangsu Provincial Key Research & Development Plan

General Project of Jiangsu Provincial Health Commission

Publisher

SAGE Publications

Subject

Cancer Research,Oncology

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