Diffuse Kaposi sarcoma with oral involvement in a person diagnosed with human immunodeficiency virus/acquired immune deficiency syndrome: A case report-Reference-Cited by-同舟云学术

Diffuse Kaposi sarcoma with oral involvement in a person diagnosed with human immunodeficiency virus/acquired immune deficiency syndrome: A case report

Published:2024-01 Issue: Volume:12 Page:
ISSN:2050-313X
Container-title:SAGE Open Medical Case Reports
language:en
Short-container-title:SAGE Open Medical Case Reports

Author:

Berrezouga Latifa¹²³^ORCID,Alouani Nada¹²³^ORCID,Kooli Ikbel⁴^ORCID,Bellalah Ahlem⁵,Chakroun Mohamed⁴

Affiliation:

1. Department of Microbiology and Immunology, Faculty of Dental Medicine, University of Monastir, Monastir, Tunisia

2. Department of Endodontics, Dental Clinic, University of Monastir, Tunisia

3. Laboratory of Medical and Molecular Parasitology and Mycology LR12ES09, Faculty of Pharmacy, University of Monastir, Tunisia

4. Department of Infectious Diseases, F. Bourguiba Teaching Hospital, University of Monastir, Monastir, Tunisia

5. Laboratory of Cytology and Histopathology, F. Bourguiba Teaching Hospital, University of Monastir, Monastir, Tunisia

Abstract

Kaposi’s sarcoma is a well-known multifocal vascular tumor initially described by pathologist Moritz Kaposi. This report presents the case of a 38-year-old bisexual male who consulted the infectious diseases department with non-itchy maculopapular and purpuric lesions on the skin with the involvement of the oral mucosa, suggesting a diagnosis of Kaposi’s sarcoma. Biological and radiological investigations were performed. The patient was found to be human immunodeficiency virus positive with a viral load of 251.000/mL and a CD4 count of 182/mm3. In addition, secondary syphilis was diagnosed. Histopathological examinations confirmed HHV-8 KS. The patient was treated with Extencilline® and antiretroviral therapy. After 10 months of chemotherapy, a favorable outcome was noted with complete resolution of skin and oral mucosa lesions.

Funder

International Association for Dental Research

Publisher

SAGE Publications

Link

http://journals.sagepub.com/doi/pdf/10.1177/2050313X241235815

Reference17 articles.

1. Kumar V, Abbas AK, Aster JC. Robbins & Cotran pathologic basis of disease.10th ed., https://www.elsevier.com/books/robbins-and-cotran-pathologic-basis-of-disease/kumar/978-0-323-53113-9 (2020).

2. Changing incidence of AIDS-defining illnesses in the era of antiretroviral combination therapy

3. Epidemiology of Kaposi’s Sarcoma

4. Kaposi's sarcoma: An update

5. Kaposi’s sarcoma: a 10-year experience with 248 patients at a single tertiary care hospital in Tanzania