Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery

Author:

Passias Peter G.1ORCID,Williamson Tyler K.2ORCID,Kummer Nicholas A.1ORCID,Pellisé Ferran3,Lafage Virginie4ORCID,Lafage Renaud5ORCID,Serra-Burriel Miguel6,Smith Justin S.7,Line Breton8ORCID,Vira Shaleen9,Gum Jeffrey L.10ORCID,Haddad Sleiman3,Sánchez Pérez-Grueso Francisco Javier11,Schoenfeld Andrew J.12,Daniels Alan H.13,Chou Dean14,Klineberg Eric O.15,Gupta Munish C.16ORCID,Kebaish Khaled M.17ORCID,Kelly Michael P.18,Hart Robert A.19,Burton Douglas C.20,Kleinstück Frank21,Obeid Ibrahim22,Shaffrey Christopher I.23,Alanay Ahmet24,Ames Christopher P.14,Schwab Frank J.4,Hostin Richard A.25,Bess Shay8,

Affiliation:

1. Departments of Orthopedic and Neurological Surgery, NYU Langone Orthopedic Hospital, New York Spine Institute, NY, NY, USA

2. Department of Orthopaedic Surgery, University of Texas Health San Antonio, San Antonio, TX, USA

3. Spine Surgery Unit, Vall d’Hebron Hospital, Barcelona, Spain

4. Department of Orthopaedics, Lenox Hill Hospital, New York, NY, USA

5. Department of Orthopaedics, Hospital for Special Surgery, New York, NY, USA

6. Center for Research in Health and Economics, Universitat Pompeu Fabra, Barcelona, Spain

7. Department of Neurosurgery, University of Virginia Medical Center, Charlottesville, VA, USA

8. Denver International Spine Center, Presbyterian St. Luke’s/Rocky Mountain Hospital for Children, Denver, CO, USA

9. Department of Orthopedic Surgery, UT Southwestern Medical Center, Dallas, TX, USA

10. Norton Leatherman Spine Center, Louisville, KY, USA

11. Spine Surgery Unit, Hospital Universitario La Paz, Madrid, Spain

12. Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA

13. Department of Orthopaedic Surgery, Warren Alpert School of Medicine, Brown University, Providence, RI, USA

14. Department of Neurosurgery, University of California, San Francisco, CA, USA

15. Department of Orthopedic Surgery, University of California Davis, Sacramento, CA, USA

16. Department of Orthopaedic Surgery, Washington University in St. Louis, Missouri, USA

17. Department of Orthopaedic Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD, USA

18. Department of Orthopaedic Surgery, Rady Children’s Hospital, San Diego, CA, USA

19. Department of Orthopaedic Surgery, Swedish Neuroscience Institute, Seattle, WA, USA

20. Department of Orthopaedic Surgery, University of Kansas Medical Center, Kansas City, KS, USA

21. Spine Center Division, Department of Orthopedics and Neurosurgery, Schulthess Klinik, Zürich, Switzerland

22. Spine Surgery Unit, Bordeaux University Hospital, Bordeaux, France

23. Spine Division, Departments of Neurosurgery and Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA

24. Department of Orthopedics and Traumatology, Acıbadem University, Istanbul, Turkey

25. Department of Orthopaedic Surgery, Baylor Scoliosis Center, Dallas, TX, USA

Abstract

Study Design/Setting Retrospective cohort study. Objective Assess the extent to which defined risk factors of adverse events are drivers of cost-utility in spinal deformity (ASD) surgery. Methods ASD patients with 2-year (2Y) data were included. Tertiles were used to define high degrees of frailty, sagittal deformity, blood loss, and surgical time. Cost was calculated using the Pearl Diver registry and cost-utility at 2Y was compared between cohorts based on the number of risk factors present. Statistically significant differences in cost-utility by number of baseline risk factors were determined using ANOVA, followed by a generalized linear model, adjusting for clinical site and surgeon, to assess the effects of increasing risk score on overall cost-utility. Results By 2 years, 31% experienced a major complication and 23% underwent reoperation. Patients with ≤2 risk factors had significantly less major complications. Patients with 2 risk factors improved the most from baseline to 2Y in ODI. Average cost increased by $8234 per risk factor (R2 = .981). Cost-per-QALY at 2Y increased by $122,650 per risk factor (R2 = .794). Adjusted generalized linear model demonstrated a significant trend between increasing risk score and increasing cost-utility (r2 = .408, P < .001). Conclusions The number of defined patient-specific and surgical risk factors, especially those with greater than two, were associated with increased index surgical costs and diminished cost-utility. Efforts to optimize patient physiology and minimize surgical risk would likely reduce healthcare expenditures and improve the overall cost-utility profile for ASD interventions. Level of evidence: III

Publisher

SAGE Publications

Subject

Neurology (clinical),Orthopedics and Sports Medicine,Surgery

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