Pediatric Stroke Rates Over 17 Years: Report From a Population-Based Study

Author:

Lehman Laura L.1,Khoury Jane C.2,Taylor J. Michael3,Yeramaneni Samrat24,Sucharew Heidi2,Alwell Kathleen5,Moomaw Charles J.5,Peariso Katrina3,Flaherty Matthew5,Khatri Pooja5,Broderick Joseph P.5,Kissela Brett M.5,Kleindorfer Dawn O.5

Affiliation:

1. Department of Neurology, Boston Children’s Hospital, MA, USA

2. Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

3. Division of Neurology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

4. Center for Clinical Effectiveness, Baylor Scott & White Health, Dallas, TX, USA

5. Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA

Abstract

We previously published rates of pediatric stroke using our population-based Greater Cincinnati Northern Kentucky Stroke Study (GCNK) for periods July 1993–June 1994 and 1999. We report population-based rates from 2 additional study periods: 2005 and 2010. We identified all pediatric strokes for residents of the GCNK region that occurred in July 1, 1993–June 30, 1994, and calendar years 1999, 2005, and 2010. Stroke cases were ascertained by screening discharge ICD-9 codes, and verified by a physician. Pediatric stroke was defined as stroke in those <20 years of age. Stroke rates by study period, overall, by age and by race, were calculated. Eleven children died within 30 days, yielding an all-cause case fatality rate of 15.7% (95% confidence interval 1.1%, 26.4%) with 3 (27.3%) ischemic, 6 (54.5%) hemorrhagic, and 2 (18.2%) unknown stroke type. The pediatric stroke rate of 4.4 per 100 000 in the GCNK study region has not changed over 17 years.

Funder

National Institute of Neurological Disorders and Stroke

Publisher

SAGE Publications

Subject

Clinical Neurology,Pediatrics, Perinatology, and Child Health

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